US 12,102,524 B2
Light adjustable intraocular lens with a modulable absorption front protection layer
Ilya Goldshleger, Ladera Ranch, CA (US); John Kondis, Irvine, CA (US); and Ritu Shrestha, Santa Ana, CA (US)
Assigned to RxSight, Inc., Aliso Viejo, CA (US)
Filed by RxSight, Inc., Aliso Viejo, CA (US)
Filed on Jan. 25, 2022, as Appl. No. 17/583,329.
Application 17/583,329 is a continuation of application No. 16/658,142, filed on Oct. 20, 2019, granted, now 11,266,495.
Prior Publication US 2022/0142770 A1, May 12, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61F 2/16 (2006.01)
CPC A61F 2/1624 (2013.01) [A61F 2/1627 (2013.01); A61F 2/1635 (2013.01); A61F 2/1659 (2013.01); A61F 2002/1683 (2013.01); A61F 2002/16965 (2015.04); A61F 2210/0085 (2013.01); A61F 2250/0001 (2013.01)] 17 Claims
OG exemplary drawing
 
1. A modulable absorption light adjustable intraocular lens (IOL) for implantation into an eye, comprising:
a light adjustable lens that is capable of changing its optical properties upon an adjusting irradiation, including a photo-modifiable material that includes
a polymer host matrix;
at least one of monomers and macromere, capable of photo-induced polymerization;
a photoinitiator; and
dispersed ultraviolet absorbers;
a modulable absorption front protection layer, including a modulable absorption compound,
wherein the modulable absorption front protection layer includes one of
a layer in the frontal region of the light adjustable lens;
a layer attached onto the frontal region of the light adjustable lens; and
a layer deposited onto the frontal region of the light adjustable lens;
wherein the modulable absorption compound has a high-absorption conformation and a low-absorption conformation,
wherein:
the modulable absorption compound is capable of transforming from the high-absorption conformation to the low-absorption conformation upon absorbing a high-to-low modulating stimulus, and
the modulable absorption compound is capable of transforming from the low-absorption conformation to the high-absorption conformation upon absorbing a low-to-high modulating stimulus.