US 12,102,508 B2
Antimicrobial wound care dressing
Shaurya Prakash, Columbus, OH (US); Vishwanath V. Subramaniam, Westerville, OH (US); Molly Marie Bennett, Seattle, WA (US); Chandan K. Sen, Upper Arlington, OH (US); Travis Hamilton Jones, Columbus, OH (US); Emily Quinn Rosenthal, Dublin, OH (US); Shomita Steiner, Olean, NY (US); Sashwati Roy, Upper Arlington, OH (US); Joseph Dean West, Richwood, OH (US); and Piya Das Ghatak, Columbus, OH (US)
Assigned to OHIO STATE INNOVATION FOUNDATION, Columbus, OH (US)
Appl. No. 16/343,214
Filed by OHIO STATE INNOVATION FOUNDATION, Columbus, OH (US)
PCT Filed Oct. 20, 2017, PCT No. PCT/US2017/057597
§ 371(c)(1), (2) Date Apr. 18, 2019,
PCT Pub. No. WO2018/075893, PCT Pub. Date Apr. 26, 2018.
Claims priority of provisional application 62/411,089, filed on Oct. 21, 2016.
Prior Publication US 2019/0247234 A1, Aug. 15, 2019
This patent is subject to a terminal disclaimer.
Int. Cl. A61F 13/01 (2024.01); A61F 13/00 (2024.01); A61F 13/05 (2024.01); A61N 1/04 (2006.01); A61N 1/08 (2006.01); A61N 1/20 (2006.01); A61N 1/32 (2006.01)
CPC A61F 13/01008 (2024.01) [A61F 13/00051 (2013.01); A61F 13/05 (2024.01); A61N 1/0468 (2013.01); A61N 1/0484 (2013.01); A61N 1/08 (2013.01); A61N 1/205 (2013.01); A61N 1/32 (2013.01); A61F 2013/00238 (2013.01); A61F 2013/00297 (2013.01)] 6 Claims
OG exemplary drawing
 
1. A method of treating a bacterial infection in a wound, the method comprising:
applying an antimicrobial dressing to the wound, said antimicrobial dressing comprising:
a substrate;
at least one pair of electrodes positioned on or within the substrate, wherein the at least pair of electrodes comprise a conductive anode configured to be in contact with at least a first portion of the wound and a conductive cathode configured to be in contact with at least a second portion of the wound; and
a plurality of electrodes in a spaced pattern on the substrate, wherein at least a portion of the plurality of electrodes in the spaced pattern are configured to be in contact with the wound;
inducing, by an energy source configured to be connected to the at least one pair of electrodes, an electrical current to flow from the conductive anode, through the wound, to the conductive cathode, wherein the energy source configured to be connected to the at least one pair of electrodes comprises the portion of the plurality of electrodes in the spaced pattern on the substrate that are configured to be in contact with the wound, a first subset of the plurality of electrodes connected in electrical series with the anode and a second set of the plurality of electrodes connected in electrical series with the cathode, and the plurality of electrodes are comprised of a biocompatible reduction/oxidation reaction material such that a voltage differential is created between the anode and the cathode, wherein said voltage differential causes the electrical current to flow from the conductive anode, through the wound, to the conductive cathode; and
applying a therapeutically effective amount of an electric current to the wound from the antimicrobial dressing.