US 12,102,464 B2
Bone age estimation method and apparatus
Byung Duk Ahn, Seoul (KR); In Seok Song, Seoul (KR); Yoon-Ji Kim, Seoul (KR); Jae Gul Choo, Gyeonggi-do (KR); Jin Hee Kim, Seoul (KR); and Tae Sung Kim, Seoul (KR)
Assigned to KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, Seoul (KR)
Appl. No. 17/763,103
Filed by KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, Seoul (KR)
PCT Filed Dec. 15, 2020, PCT No. PCT/KR2020/018320
§ 371(c)(1), (2) Date Mar. 23, 2022,
PCT Pub. No. WO2021/149918, PCT Pub. Date Jul. 29, 2021.
Claims priority of application No. 10-2020-0009524 (KR), filed on Jan. 23, 2020; and application No. 10-2020-0066130 (KR), filed on Jun. 2, 2020.
Prior Publication US 2022/0386976 A1, Dec. 8, 2022
Int. Cl. A61B 6/50 (2024.01); A61B 6/00 (2024.01); A61B 6/46 (2024.01); G06T 7/00 (2017.01); G06T 7/64 (2017.01)
CPC A61B 6/505 (2013.01) [A61B 6/463 (2013.01); A61B 6/469 (2013.01); A61B 6/5217 (2013.01); A61B 6/54 (2013.01); G06T 7/0012 (2013.01); G06T 7/64 (2017.01); G06T 2207/10116 (2013.01); G06T 2207/20081 (2013.01); G06T 2207/20101 (2013.01); G06T 2207/30012 (2013.01)] 15 Claims
OG exemplary drawing
 
1. A bone age estimation method, comprising the steps of:
extracting a region of interest including a cervical spine region from a lateral cephalometric radiographic image obtained by imaging a subject's cervical spine, by using a first deep learning model;
extracting landmarks from the extracted region of interest by using a second deep learning model;
displaying landmarks as points in the region of interest on the basis of a user input selecting landmarks to be displayed and landmarks to not be displayed from the extracted landmarks;
calculating a landmark numerical value on the basis of the displayed landmarks; and
providing maturity information of a maturation stage of the cervical spine on the basis of the calculated landmark numerical value,
wherein the step of providing maturity information includes:
a step of visually providing the maturity information of the cervical spine on the basis of a gender of the subject, age-specific standardization information for a concavity of a fourth cervical spine lower border corresponding to the gender of the subject, and a concavity ratio of the fourth cervical spine lower border of the subject, and
a step of providing a graph corresponding to the age-specific standardization information and a graph corresponding to the concavity ratio of the fourth cervical spine lower border of the subject to be overlaid.