US 12,102,389 B2
En face retinal vessel shadow view optical coherence tomography images
Cynthia Toth, Durham, NC (US); Kai Seely, Durham, NC (US); Vincent Tai, Durham, NC (US); Stephanie Chiu, Durham, NC (US); Katrina Winter, Durham, NC (US); and Ryan Imperio, Durham, NC (US)
Assigned to DUKE UNIVERSITY, Durham, NC (US)
Appl. No. 17/767,776
Filed by Duke University, Durham, NC (US)
PCT Filed Oct. 9, 2020, PCT No. PCT/US2020/055001
§ 371(c)(1), (2) Date Apr. 8, 2022,
PCT Pub. No. WO2021/072204, PCT Pub. Date Apr. 15, 2021.
Claims priority of provisional application 62/913,863, filed on Oct. 11, 2019.
Prior Publication US 2024/0081642 A1, Mar. 14, 2024
Int. Cl. A61B 3/12 (2006.01); A61B 3/00 (2006.01); A61B 3/10 (2006.01); G06T 7/00 (2017.01); G06T 7/12 (2017.01)
CPC A61B 3/1225 (2013.01) [A61B 3/0025 (2013.01); A61B 3/102 (2013.01); G06T 7/0012 (2013.01); G06T 7/12 (2017.01); G06T 2207/10101 (2013.01); G06T 2207/20081 (2013.01); G06T 2207/30041 (2013.01); G06T 2207/30101 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A method comprising:
receiving a volumetric optical coherence tomography (OCT) scan of a patient;
segmenting the volumetric OCT scan to determine layer boundaries;
delineating a boundary of interest based on the determined layer boundaries of the segmented volumetric OCT scan;
extracting en face vascular information from the segmented volumetric OCT scans to create a retinal vessel shadow view (RVSV)-OCT image by:
determining a first offset from the boundary of interest and a second offset from the boundary of interest;
extracting volumetric data from an area between the first offset and the second offset to create a three-dimensional volume; and
identifying a two-dimensional surface from the three-dimensional volume, the two-dimensional surface being the RVSV-OCT image; and
providing the RVSV-OCT image for analysis.