US 11,774,401 B2
Chemical sensor array having multiple sensors per well
Jonathan M. Rothberg, Guilford, CT (US); Keith G Fife, Palo Alto, CA (US); Jordan Owens, Austin, TX (US); and James Bustillo, Castro Valley, CA (US)
Assigned to Life Technologies Corporation, Carlsbad, CA (US)
Filed by Life Technologies Corporation, Carlsbad, CA (US)
Filed on Oct. 7, 2022, as Appl. No. 18/45,106.
Application 17/070,142 is a division of application No. 16/663,052, filed on Oct. 24, 2019, granted, now 10,816,504, issued on Oct. 27, 2020.
Application 16/663,052 is a division of application No. 14/293,247, filed on Jun. 2, 2014, granted, now 10,458,942, issued on Oct. 29, 2019.
Application 18/045,106 is a continuation of application No. 17/070,142, filed on Oct. 14, 2020, granted, now 11,499,938.
Claims priority of provisional application 61/833,375, filed on Jun. 10, 2013.
Prior Publication US 2023/0125333 A1, Apr. 27, 2023
Int. Cl. G01N 27/414 (2006.01); C12Q 1/6874 (2018.01); H01L 29/66 (2006.01)
CPC G01N 27/4145 (2013.01) [C12Q 1/6874 (2013.01); G01N 27/414 (2013.01); H01L 29/66825 (2013.01)] 20 Claims
OG exemplary drawing
 
1. An apparatus, comprising:
a chemically-sensitive field effect transistor (chemFET) sensor device comprising:
an array of reaction regions;
at least two chemFET sensors coupled to each reaction region of the array of reaction regions, wherein each chemFET sensor of the at least two chemFET sensors comprises a chemFET and a row select transistor; and
a floating gate common to the at least two chemFET sensors and in communication with each respective reaction region;
a row select circuit for biasing each row select transistor of each chemFET sensor of the at least two chemFET sensors for each reaction region in the array of reaction regions;
a column output circuit for coupling each chemFET of the at the least two chemFET sensors for each reaction region in the array of reaction regions to a respective column line in response to biasing each respective row select transistor; and
an array controller comprising memory for storage of data and software applications, and a processor for accessing data and executing applications.