Integrated human organ-on-chip microphysiological systems
Donald E. Ingber, Boston, MA (US); Anthony Bahinski, Wilmington, DE (US); Robert Cunningham, Cohasset, MA (US); Josue A. Goss, Somerville, MA (US); Geraldine A. Hamilton, Cambridge, MA (US); Christopher David Hinojosa, Cambridge, MA (US); Daniel Levner, Boston, MA (US); and Kevin Kit Parker, Waitham, MA (US)
Assigned to PRESIDENT AND FELLOWS OF HARVARD COLLEGE, Cambridge, MA (US)
Filed by PRESIDENT AND FELLOWS OF HARVARD COLLEGE, Cambridge, MA (US)
Filed on Jan. 11, 2021, as Appl. No. 17/146,264.
Application 17/146,264 is a continuation of application No. 16/134,746, filed on Sep. 18, 2018, granted, now 10,954,482.
Application 16/134,746 is a continuation of application No. 14/928,039, filed on Oct. 30, 2015, abandoned.
Application 14/928,039 is a continuation of application No. 14/362,841, granted, now 9,725,687, issued on Aug. 8, 2017, previously published as PCT/US2012/068725, filed on Dec. 10, 2012.
Claims priority of provisional application 61/569,004, filed on Dec. 9, 2011.
Prior Publication US 2021/0388301 A1, Dec. 16, 2021
1. A device, comprising hepatocytes on a first side of a membrane, and microvascular endothelial cells on a second side of said membrane, with Kupffer cells positioned under said endothelial cells.
