CPC C07D 213/74 (2013.01) [C07D 401/04 (2013.01); C07D 401/12 (2013.01); C07D 403/04 (2013.01); C07D 403/14 (2013.01); C07D 405/12 (2013.01)] | 4 Claims |
1. A compound according to Formula I or pharmaceutically acceptable salt thereof, wherein:
![]() wherein:
R1 is aryl optionally substituted with one or more groups selected independently from: H, alkyl, cycloalkyl, alkenyl, aryl, heteroaryl, benzyl, alkoxy, halogen, cyan, nitro, amino, hydroxyl, CF3 or —OCF3, wherein alkyl is optionally substituted with one or more chosen substituents chosen from: hydroxyl, cyan, amino, or halogen;
X is CH2;
W is CH;
Y is CH;
Z is CH;
Q is
![]() R2 is H; and
R3 is selected from: H, alkyl, heteroaryl, heterocyclyl, heterocyclyl-alkyl, and hydroxyl-alkyl; and each group is optionally substituted with one or more groups selected independently from: alkyl, cycloalkyl, alkenyl, aryl, heteroaryl, benzyl, alkoxy, halogen, cyan, nitro, amino, hydroxyl, CF3 or —OCF3;
or R2 and R3 together form a 4-12 membered cycloalkyl ring, and the -12 membered cycloalkyl is optionally substituted with one or more groups selected independently from: alkyl, cycloalkyl, alkenyl, aryl, heteroaryl, benzyl, alkoxy, halogen, cyan, nitro, amino, hydroxyl, CF3 or —OCF3;
R4 is independently chosen from H, alkyl, alkoxy, halogen, cyan, amino, A hydroxyl, nitro, CF3 or —OCF3.
|