CPC A61M 5/2033 (2013.01) [A61K 9/0024 (2013.01); A61M 5/30 (2013.01); A61M 2005/202 (2013.01); A61M 2202/0007 (2013.01); A61M 2202/30 (2013.01); A61M 2210/1042 (2013.01)] | 32 Claims |
1. A self-righting article, comprising:
a self-actuating component comprising a spring and a support material adapted to maintain the spring in at least a partially compressed state, wherein the support material is configured for at least partial degradation in a biological fluid;
a chamber comprising a liquid active pharmaceutical agent (or non-active to serve as contrast or cushion); and
a tissue interfacing component operably linked to the self-actuating component, the tissue interfacing component comprising an inlet, an outlet, and a channel fluidically connected to the inlet and the outlet;
wherein the chamber is configured to be in fluidic communication with the inlet upon activation of the self-actuating component, and
wherein when the self-righting article is at least partially supported by the tissue of the subject, the self-righting article orients in a direction to allow the tissue interfacing component to release at least a portion of the active pharmaceutical agent into the tissue.
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