CPC A61K 31/69 (2013.01) [A61K 31/05 (2013.01); A61K 45/06 (2013.01); A61P 1/00 (2018.01); A61P 19/02 (2018.01); A61P 35/00 (2018.01); C07F 5/027 (2013.01); A61K 2300/00 (2013.01)] | 20 Claims |
1. A compound defined by Formula IV, or a pharmaceutically acceptable salt thereof:
![]() wherein
Q is a substituted or unsubstituted dicarba-closo-dodecaborane cluster, and
![]() are attached to Q in a para configuration;
the dotted line to Y indicates that the bond can be a single bond or a double bond, as valence permits;
X is OH, NHR2, SH, or S(O)(O)NHR2;
Y is O, OR2′, NHR2, SH, or S(O)(O)NHR2;
R6 is substituted or unsubstituted C2-C20 alkyl, substituted or unsubstituted C2-C20 alkenyl, substituted or unsubstituted C2-C20 alkynyl, substituted or unsubstituted C2-C20 alkylaryl, substituted or unsubstituted C4-C20 alkylcycloalkyl, or NR3R4;
R2 is H, OH, halogen, or substituted or unsubstituted C1-C4 alkyl;
R2′ is H or substituted or unsubstituted C1-C4 alkyl; and
R3 and R4 are independently selected from substituted or unsubstituted C1-C20 alkyl, substituted or unsubstituted C2-C20 alkenyl, substituted or unsubstituted C2-C20 alkynyl, substituted or unsubstituted C2-C20 alkylaryl, substituted or unsubstituted C4-C20 alkylcycloalkyl, or substituted or unsubstituted C1-C20 acyl.
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