CPC A61K 31/497 (2013.01) [A61K 31/13 (2013.01); A61K 31/416 (2013.01); A61K 31/4439 (2013.01); A61K 31/485 (2013.01); A61K 31/675 (2013.01); A61K 45/06 (2013.01); C07D 231/54 (2013.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 405/14 (2013.01); C07F 9/65583 (2013.01)] | 11 Claims |
1. A method for the management of pain in an individual in need thereof, comprising administering to said individual, a composition comprising a compound which is:
![]() and one or more known pharmaceutical agents selected from: analgesic agents, antidiabetic agents, osteoarthritis agents, and anticancer agents; and a pharmaceutically acceptable carrier;
wherein the pain is chosen from: bone and joint pain, pain associated with osteoarthritis, hyperalgesia, allodynia, inflammatory pain, inflammatory hyperalgesia, neuropathic pain, neuropathic hyperalgesia, acute nociception, muscle pain, dental pain, migraine and other headache pain, pain that occurs as an adverse effect of therapeutics in an individual, and pain associated with a disorder selected from: cancer, multiple sclerosis, allergic reactions, nephritic syndrome, scleroderma, thyroiditis, diabetic neuropathy, fibromyalgia, HIV related-neuropathy, sciatica, and an autoimmune condition.
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