US 11,771,543 B2
Poly(ester urea) adhesion barriers for use in the treatment of hernia-mesh repair
Matthew Becker, Chapel Hill, NC (US); Nathan Z. Dreger, Copley, OH (US); Zachary K. Zander, Sheffield Village, OH (US); Trenton Parsell, Lafayette, IN (US); and Michael Hiles, Lafayette, IN (US)
Assigned to The University of Akron, Akron, OH (US); and Cook Medical Technologies LLC, Bloomington, IN (US)
Appl. No. 17/52,982
Filed by THE UNIVERSITY OF AKRON, Akron, OH (US); and COOK MEDICAL TECHNOLOGIES LLC, Bloomington, IN (US)
PCT Filed May 7, 2019, PCT No. PCT/US2019/031025
§ 371(c)(1), (2) Date Nov. 4, 2020,
PCT Pub. No. WO2020/226622, PCT Pub. Date Nov. 12, 2020.
Prior Publication US 2021/0212807 A1, Jul. 15, 2021
Int. Cl. A61F 2/00 (2006.01); A61F 2/02 (2006.01); C08G 63/685 (2006.01)
CPC A61F 2/0077 (2013.01) [A61F 2/0063 (2013.01); A61F 2/02 (2013.01); C08G 63/685 (2013.01); A61F 2002/0091 (2015.04)] 34 Claims
OG exemplary drawing
 
1. A poly(ester urea) (PEU) terpolymer for use as an adhesion barrier comprising the reaction product of one or more first amine protected amino acid-based diester monomers, one or more second amine protected amino acid-based diester monomers, one or more amine protected L-tyrosine-based allyloxy diester monomers, a urea bond forming compound and one or more thiol functionalized zwitterionic compounds.