US 11,771,349 B2
Determining tissue oxygen saturation using monte carlo and iterative techniques
Kate LeeAnn Bechtel, Pleasant Hill, CA (US); and H. Keith Nishihara, Los Altos, CA (US)
Assigned to ViOptix, Inc., Newark, CA (US)
Filed by ViOptix, Inc., Newark, CA (US)
Filed on Jun. 16, 2020, as Appl. No. 16/903,315.
Application 16/903,315 is a division of application No. 15/895,904, filed on Feb. 13, 2018, granted, now 10,682,080.
Application 15/895,904 is a division of application No. 15/163,565, filed on May 24, 2016, granted, now 10,213,142, issued on Feb. 26, 2019.
Application 15/163,565 is a continuation of application No. 13/887,220, filed on May 3, 2013, granted, now 9,345,439, issued on May 24, 2016.
Claims priority of provisional application 61/682,146, filed on Aug. 10, 2012.
Claims priority of provisional application 61/642,399, filed on May 3, 2012.
Claims priority of provisional application 61/642,389, filed on May 3, 2012.
Claims priority of provisional application 61/642,395, filed on May 3, 2012.
Claims priority of provisional application 61/642,393, filed on May 3, 2012.
Prior Publication US 2020/0305775 A1, Oct. 1, 2020
This patent is subject to a terminal disclaimer.
Int. Cl. A61B 5/1455 (2006.01); A61B 90/00 (2016.01); A61B 5/00 (2006.01); A61B 5/1495 (2006.01); A61M 35/00 (2006.01); A61B 5/145 (2006.01); A61B 90/11 (2016.01); A61B 5/1459 (2006.01); A61B 90/30 (2016.01)
CPC A61B 5/14551 (2013.01) [A61B 5/0059 (2013.01); A61B 5/0075 (2013.01); A61B 5/1455 (2013.01); A61B 5/1459 (2013.01); A61B 5/1495 (2013.01); A61B 5/14546 (2013.01); A61B 5/14552 (2013.01); A61B 5/72 (2013.01); A61B 5/7246 (2013.01); A61B 5/7282 (2013.01); A61B 5/74 (2013.01); A61B 5/742 (2013.01); A61B 5/7405 (2013.01); A61B 5/7475 (2013.01); A61B 90/11 (2016.02); A61B 90/39 (2016.02); A61M 35/003 (2013.01); A61B 2090/065 (2016.02); A61B 2090/306 (2016.02); A61B 2090/395 (2016.02); A61B 2560/0431 (2013.01); A61B 2560/0475 (2013.01); A61B 2562/0271 (2013.01); A61B 2562/166 (2013.01)] 25 Claims
OG exemplary drawing
 
1. A method comprising:
emitting light from a first light source and a second light source of a tissue oximetry device into a tissue;
using a plurality of detectors of the tissue oximetry device to detect reflected light from the tissue resulting from the emitted light;
using a processor, generating reflectance data points for the tissue based on detecting the light by the plurality of detectors;
for a coarse grid, determining a first subset of simulated reflectance curves from a plurality of simulated reflectance curves stored in the tissue oximetry device;
for the coarse grid, based on the first subset of simulated reflectance curves, fitting the reflectance data points to determine a fitting to one simulated reflectance curve of the first sub set;
for a fine grid, determining a second subset of simulated reflectance curves from the simulated reflectance curves stored in the tissue oximetry device based on the one simulated reflectance curve of the first subset determined during the coarse grid determination;
from the fine grid determination, determining a peak surface array of absorption coefficients and reflection coefficients; and
using the reflection coefficients, determining an oxygen saturation of the tissue.