US 12,427,097 B2
Oral care compositions comprising monodentate and polydentate ligand
William Michael Glandorf, Mason, OH (US); Andrew Frederic Groth, Mason, OH (US); Samuel James St. John, Cincinnati, OH (US); and Ross Strand, Singapore (SG)
Assigned to The Procter & Gamble Company, Cincinnati, OH (US)
Filed by The Procter & Gamble Company, Cincinnati, OH (US)
Filed on Sep. 16, 2024, as Appl. No. 18/886,244.
Application 18/886,244 is a continuation of application No. 17/308,081, filed on May 5, 2021, abandoned.
Claims priority of provisional application 63/020,032, filed on May 5, 2020.
Prior Publication US 2025/0009616 A1, Jan. 9, 2025
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 8/27 (2006.01); A61K 8/06 (2006.01); A61K 8/21 (2006.01); A61K 8/25 (2006.01); A61K 8/29 (2006.01); A61K 8/362 (2006.01); A61K 8/365 (2006.01); A61K 8/37 (2006.01); A61K 8/55 (2006.01); A61K 8/60 (2006.01); A61K 8/73 (2006.01); A61Q 11/00 (2006.01)
CPC A61K 8/27 (2013.01) [A61K 8/06 (2013.01); A61K 8/21 (2013.01); A61K 8/25 (2013.01); A61K 8/29 (2013.01); A61K 8/362 (2013.01); A61K 8/365 (2013.01); A61K 8/37 (2013.01); A61K 8/55 (2013.01); A61K 8/60 (2013.01); A61K 8/73 (2013.01); A61Q 11/00 (2013.01); A61K 2800/48 (2013.01); A61K 2800/74 (2013.01)] 17 Claims
OG exemplary drawing
 
1. An oral care composition comprising:
(a) tin, wherein the tin comprises stannous fluoride, stannous chloride, or combinations thereof;
(b) monodentate ligand, wherein the monodentate ligand comprises a compound comprising a single functional group capable of chelating tin, and wherein the monodentate ligand comprises carboxylic acid or a salt thereof, wherein the carboxylic acid comprises aliphatic carboxylic acid, sugar acid, salts thereof, or combinations thereof;
(c) polydentate ligand, wherein the polydentate ligand comprises a compound comprising at least two functional groups capable of chelating tin, wherein the polydentate ligand comprises a bidentate ligand and/or a tridentate ligand, and wherein the polydentate ligand comprises carboxylic acid, phosphate, polyphosphate, or combinations thereof, wherein the carboxylic acid comprises dicarboxylic acid, tricarboxylic acid, salts thereof, or combinations thereof; and
(d) a fluoride source,
wherein the oral care composition has a tin to monodentate ligand to polydentate ligand molar ratio of 1:1:1 to 1:2.5:2.5.