US 12,426,822 B2
Method and a system for producing a standard 12-lead ECG
Martin Ugander, Cremorne (AU); and Teddy Curtis, London (GB)
Assigned to KOZOR UGANDER CAPITAL PTY LIMITED, Sydney (AU)
Appl. No. 18/246,901
Filed by KOZOR UGANDER CAPITAL PTY LIMITED, Sydney (AU)
PCT Filed Sep. 24, 2021, PCT No. PCT/EP2021/076338
§ 371(c)(1), (2) Date Mar. 28, 2023,
PCT Pub. No. WO2022/063975, PCT Pub. Date Mar. 31, 2022.
Claims priority of application No. 20198752 (EP), filed on Sep. 28, 2020.
Prior Publication US 2023/0363684 A1, Nov. 16, 2023
Int. Cl. A61B 5/00 (2006.01); A61B 5/282 (2021.01)
CPC A61B 5/282 (2021.01) [A61B 5/6823 (2013.01); A61B 5/6824 (2013.01)] 16 Claims
OG exemplary drawing
 
1. A computer-implemented method for producing a standard 12-lead ECG formed by three standard limb leads I, II, III, three standard augmented limb leads aVR, aVL, aVF, and six standard precordial leads V1 to V6, from fifteen asynchronous, sequentially acquired leads, including three acquired limb leads I, II, and III, termed acquired leads I-III, and twelve acquired arm-referenced chest leads CR1-CR6 and CL1-CL6, termed acquired leads CR1-CR6 and CL1-CL6;
wherein, for integer i equal from 1 to 6, each pair of acquired leads CRi and CLi of acquired leads CR1-CR6 and CL1-CL6 represent voltage differences acquired between a right arm and a left arm, respectively, and a common chest position Ci associated with a corresponding standard precordial lead Vi,
said method comprising:
creating time-aligned limb leads I, II and III, termed time-aligned leads I-III, from acquired leads I-III, by using the formula lead II−lead I=lead Ill;
calculating three time-aligned augmented limb leads aVR, aVL, and aVF from time-aligned leads I-III;
performing, for integer i equal from 1 to 6, one of (a) and (b):
(a) creating a time-aligned arm-referenced chest lead CRi, termed time-aligned CRi, by time-aligning acquired lead CRi with acquired lead I such that a calculated difference CRi−I, representing a calculated arm-referenced chest lead CLi, termed calculated lead CLi, has an optimal agreement with acquired lead CLi,
(b) creating a time-aligned acquired arm-referenced chest lead CLi, termed time-aligned CLi, by time-aligning acquired lead CLi with acquired lead I such that a calculated sum CLi+I, representing a calculated arm-referenced chest lead CRi, termed calculated lead CRi, has an optimal agreement with acquired lead CRi;
and
calculating, for integer i equal from 1 to 6, a time-aligned precordial lead Vi from time-aligned lead I, one of time-aligned lead II and time-aligned lead III, and one of time-aligned lead CRi and time-aligned lead CLi, for forming time-aligned precordial leads V1-V6;
wherein time-aligned leads I-III, time-aligned augmented leads limb leads aVR, aVL, and aVF, and time-aligned precordial leads V1-V6 together form a standard 12-lead ECG.