US 11,766,420 B2
Application of PI4KIIIA protein and related membrane protein complex in treating alzheimer's disease
Fude Huang, Shanghai (CN); Xiao Zhang, Shanghai (CN); Wenan Wang, Shanghai (CN); Le Zhang, Shanghai (CN); Lixiang Jiang, Shanghai (CN); Tong Zhu, Shanghai (CN); Haiyan Liu, Shanghai (CN); Yudong Zhou, Zhejiang (CN); Yang He, Zhejiang (CN); and Wanguo Wei, Shanghai (CN)
Assigned to JIANGSU NUO-BETA PHARMACEUTICAL TECHNOLOGY CO. LTD., Nantong (CN)
Appl. No. 15/570,681
Filed by Jiangsu Nuo-Beta Pharmaceutical Technology Co., Ltd., Nantong Jiangsu (CN)
PCT Filed May 3, 2016, PCT No. PCT/CN2016/080907
§ 371(c)(1), (2) Date Jun. 4, 2019,
PCT Pub. No. WO2016/173562, PCT Pub. Date Nov. 3, 2016.
Claims priority of application No. PCT/CN2015/078058 (WO), filed on Apr. 30, 2015.
Prior Publication US 2019/0314321 A1, Oct. 17, 2019
Int. Cl. A61K 31/285 (2006.01); A61K 31/341 (2006.01); A61K 31/343 (2006.01); A61K 31/381 (2006.01); A61K 31/404 (2006.01); A61K 31/42 (2006.01); A61K 31/4406 (2006.01); A61K 31/47 (2006.01); A61K 31/5375 (2006.01); A61K 31/538 (2006.01); A61K 31/54 (2006.01); A61K 38/45 (2006.01); A61K 38/00 (2006.01); C07K 14/395 (2006.01); C07K 14/415 (2006.01); C07K 16/12 (2006.01); C07K 16/18 (2006.01); C07K 16/40 (2006.01)
CPC A61K 31/285 (2013.01) [A61K 31/341 (2013.01); A61K 31/343 (2013.01); A61K 31/381 (2013.01); A61K 31/404 (2013.01); A61K 31/42 (2013.01); A61K 31/4406 (2013.01); A61K 31/47 (2013.01); A61K 31/538 (2013.01); A61K 31/5375 (2013.01); A61K 31/54 (2013.01); A61K 38/45 (2013.01); C07K 14/395 (2013.01); C07K 14/415 (2013.01); C07K 16/1203 (2013.01); C07K 16/18 (2013.01); C07K 16/40 (2013.01); C12Y 207/01067 (2013.01); A61K 38/00 (2013.01)] 5 Claims
 
1. A method for treating ameliorating or inhibiting Alzheimer's disease and its symptoms in a subject in need thereof, the method comprising administering to the subject a PI4KIIIα inhibitor.