	US 11,766,392 B2
	Minoxidil adjuvant therapies
Ofer A. Goren, Irvine, CA (US); and John McCoy, Irvine, CA (US)
Assigned to JUPITER WELLNESS, INC., Jupiter, FL (US)
Filed by JUPITER WELLNESS, INC., Jupiter, FL (US)
Filed on Oct. 4, 2019, as Appl. No. 16/593,577.
Claims priority of provisional application 62/895,627, filed on Sep. 4, 2019.
Claims priority of provisional application 62/849,598, filed on May 17, 2019.
Claims priority of provisional application 62/800,065, filed on Feb. 1, 2019.
Claims priority of provisional application 62/756,293, filed on Nov. 6, 2018.
Claims priority of provisional application 62/741,990, filed on Oct. 5, 2018.
Prior Publication US 2021/0059920 A1, Mar. 4, 2021
Int. Cl. A61K 8/49 (2006.01); A61K 8/35 (2006.01); A61Q 7/00 (2006.01); A61Q 7/02 (2006.01); A61K 8/84 (2006.01); A61K 8/96 (2006.01); A61K 31/506 (2006.01); A61K 9/00 (2006.01); A61K 8/33 (2006.01); A61K 31/11 (2006.01); A61K 31/353 (2006.01); A61K 31/122 (2006.01); A61K 9/08 (2006.01); A61K 8/37 (2006.01); A61K 31/225 (2006.01); A61K 9/16 (2006.01); A61K 9/51 (2006.01); A61P 17/14 (2006.01); A61M 5/142 (2006.01)

CPC A61K 8/4953 (2013.01) [A61K 8/33 (2013.01); A61K 8/35 (2013.01); A61K 8/355 (2013.01); A61K 8/37 (2013.01); A61K 8/498 (2013.01); A61K 8/84 (2013.01); A61K 8/96 (2013.01); A61K 9/0014 (2013.01); A61K 9/08 (2013.01); A61K 9/1647 (2013.01); A61K 9/5115 (2013.01); A61K 31/11 (2013.01); A61K 31/122 (2013.01); A61K 31/225 (2013.01); A61K 31/353 (2013.01); A61K 31/506 (2013.01); A61M 5/14276 (2013.01); A61P 17/14 (2018.01); A61Q 7/00 (2013.01); A61Q 7/02 (2013.01); A61K 2800/5922 (2013.01); A61K 2800/78 (2013.01); A61K 2800/87 (2013.01)]

18 Claims

1. A method for treating alopecia, the method comprising:

administering a topical solution containing an alkalinizing agent that will increase sulfotransferase activity and increase the sulfonation capacity of the outer root sheath of hair follicles; and

applying a topical or oral dosage form of minoxidil with, prior to, or after application of the topical solution containing the alkalinizing agent,

wherein the topical solution raises the intracellular pH of cells in the outer root sheath of the hair follicles to a pH range between 7.4 and 11.