US 12,423,490 B2
Model mosaic framework for modeling glucose sensitivity
Peter Ajemba, Canyon Country, CA (US); and Keith Nogueira, Mission Hills, CA (US)
Assigned to MEDTRONIC MINIMED, INC., Northridge, CA (US)
Filed by MEDTRONIC MINIMED, INC., Northridge, CA (US)
Filed on Jan. 29, 2021, as Appl. No. 17/163,233.
Prior Publication US 2022/0245306 A1, Aug. 4, 2022
Int. Cl. A61B 5/145 (2006.01); G06F 30/27 (2020.01); G16H 10/40 (2018.01); G16H 50/20 (2018.01); G16H 50/50 (2018.01)
CPC G06F 30/27 (2020.01) [G16H 10/40 (2018.01); G16H 50/20 (2018.01); G16H 50/50 (2018.01)] 20 Claims
OG exemplary drawing
 
1. A system comprising:
memory configured to store a plurality of machine learning models, wherein each machine learning model of the plurality of machine learning models is trained using training data comprising clinical data on glucose sensitivity; and
one or more processors configured to:
partition an input signal feature space into a plurality of contiguous subspaces, the input signal feature space relating glucose sensitivity and a sensor electrical property associated with a glucose sensor device, each subspace of the plurality of contiguous subspaces associated with a respective glucose sensitivity behavior of the glucose sensor device that is modeled by a respective machine learning model in the plurality of machine learning models;
receive sensor data relating to the sensor electrical property;
input the sensor data into a machine learning model of the plurality of machine learning models, wherein the machine learning model is selected from the plurality of machine learning models based on the sensor data and a respective range of values associated with the sensor electrical property for each subspace of the plurality of contiguous subspaces;
receive an output from the machine learning model indicating the glucose sensitivity of the glucose sensor device;
determine a glucose level based on the sensor data and the glucose sensitivity; and
control delivery of insulin by an insulin delivery device based on the determined glucose level.