US 12,422,803 B2
Optimized process control
Christian Grimm, Heilbad Heiligenstadt (DE); Marek Höhse, Göttingen (DE); Johan Hultman, Malmö (SE); and Chloe Lang, Copenhagen (DK)
Assigned to Sartorius Stedim Data Analytics AB, (SE)
Appl. No. 17/433,586
Filed by Sartorius Stedim Data Analytics AB, Umea (SE)
PCT Filed Feb. 25, 2020, PCT No. PCT/EP2020/054900
§ 371(c)(1), (2) Date Aug. 24, 2021,
PCT Pub. No. WO2020/173936, PCT Pub. Date Sep. 3, 2020.
Claims priority of application No. 19159406 (EP), filed on Feb. 26, 2019.
Prior Publication US 2022/0137579 A1, May 5, 2022
Int. Cl. G05B 19/042 (2006.01); G01N 21/65 (2006.01)
CPC G05B 19/042 (2013.01) [G01N 21/65 (2013.01); G05B 2219/32191 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A computer-implemented method for controlling a process in a plurality of first scale vessels via a first process control device, wherein each of the first scale vessels contains fluid, wherein the process is for producing a chemical, pharmaceutical, biopharmaceutical and/or biological product, the method comprising:
receiving, by the first process control device, process parameters, the process parameters including process parameters to be controlled and process parameters to be measured;
controlling, by the first process control device and at least partly in parallel, the process in each of the first scale vessels;
periodically determining, prior to an assigning decision and at a first frequency, first sets of process parameter values for each of the process parameters from each of the first scale vessels;
carrying out the assigning decision by assigning corresponding ones of the first scale vessels to an analysis subset and other ones of the first scale vessels to an excluded subset in order to focus resources of the first process control device on determining process parameter values from the first scale vessels in the analysis subset;
periodically determining, after the assigning decision and at a second frequency, second sets of process parameter values for each of the process parameters from the analysis subset of the first scale vessels, wherein the second frequency is greater than the first frequency;
cease determining, by the process control device, process parameter values from the first scale vessels of the excluded subset; and
controlling, by the first process control device and at least partly in parallel, the process in the first scale vessels of the analysis subset according to the second sets of process parameter values.