	US 12,421,491 B2
	Composition for increasing biological activity of stem cells using mixture 4F
Sang Mo Kwon, Guri-si (KR); and Yeon Ju Kim, Gumi-si (KR)
Assigned to YOUTH BIO GLOBAL CO., LTD., Seoul (KR)
Filed by YOUTH BIO GLOBAL CO., LTD., Seoul (KR)
Filed on Aug. 30, 2021, as Appl. No. 17/461,209.
Application 17/461,209 is a continuation of application No. PCT/KR2020/009037, filed on Jul. 9, 2020.
Claims priority of application No. 10-2019-0082712 (KR), filed on Jul. 9, 2019.
Prior Publication US 2021/0395674 A1, Dec. 23, 2021
Int. Cl. C12N 5/00 (2006.01); A61K 31/575 (2006.01); A61K 31/7048 (2006.01); A61K 31/737 (2006.01); A61K 38/18 (2006.01); A61P 9/10 (2006.01)

CPC C12N 5/0056 (2013.01) [A61K 31/575 (2013.01); A61K 31/7048 (2013.01); A61K 31/737 (2013.01); A61K 38/1866 (2013.01); A61P 9/10 (2018.01)]

6 Claims

1. A stem cell culture medium composition containing fucoidan, a tauroursodeoxycholic acid, oleuropein, and a vascular endothelial growth factor,

wherein the fucoidan is at a concentration of 1 to 300 nM,

wherein the tauroursodeoxycholic acid is at a concentration of 17.5 to 35 μM,

wherein the oleuropein is at a concentration of 0.35 to 0.7 μM, and

wherein the vascular endothelial growth factor is at a concentration of 0.1 to 5 nM.