	US 12,421,294 B2
	Truncated epiderimal growth factor receptor (EGFRt) for transduced t cell selection
Michael C. Jensen, Duarte, CA (US)
Assigned to City of Hope, Duarte, CA (US)
Filed by City of Hope, Duarte, CA (US)
Filed on Oct. 22, 2021, as Appl. No. 17/507,996.
Application 15/431,248 is a division of application No. 14/340,512, filed on Jul. 24, 2014, granted, now 9,580,685, issued on Feb. 28, 2017.
Application 14/340,512 is a division of application No. 13/463,247, filed on May 3, 2012, granted, now 8,802,374, issued on Aug. 12, 2014.
Application 17/507,996 is a continuation of application No. 16/160,944, filed on Oct. 15, 2018, granted, now 11,155,783.
Application 16/160,944 is a continuation of application No. 15/431,248, filed on Feb. 13, 2017, granted, now 10,100,281, issued on Oct. 16, 2018.
Application 13/463,247 is a continuation of application No. PCT/US2010/055329, filed on Nov. 3, 2010.
Claims priority of provisional application 61/257,567, filed on Nov. 3, 2009.
Prior Publication US 2022/0041986 A1, Feb. 10, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. C07K 14/71 (2006.01); A61K 40/11 (2025.01); A61K 40/31 (2025.01); A61K 40/34 (2025.01); A61K 40/42 (2025.01); A61K 40/46 (2025.01); C12N 5/0783 (2010.01); C12N 9/12 (2006.01)

CPC C07K 14/71 (2013.01) [A61K 40/11 (2025.01); A61K 40/31 (2025.01); A61K 40/34 (2025.01); A61K 40/4211 (2025.01); A61K 40/46 (2025.01); C12N 5/0636 (2013.01); C12N 9/12 (2013.01); A61K 2239/31 (2023.05); C12N 2510/00 (2013.01); C12Y 207/10001 (2013.01)]

9 Claims

1. A population of human T-cells harboring a nucleic acid molecule comprising a nucleotide sequence encoding the amino acid sequence comprising amino acids 23-357 of SEQ ID NO:3 and not encoding an EGFR Domain I, an EGFR Domain II, an EGFR Juxtamembrane Domain, and an EGFR Tyrosine Kinase Domain.