Pharmaceutically effective compounds inhibiting selectively the myosin 2 isoforms
András Málnási-Csizmadia, Budapest (HU); Máté Gyimesi, Budapest (HU); András Szabó, Budapest (HU); Péter Hári, Veresegyház (HU); Suthar Sharad Kumar, Budapest (HU); Mihály Kovács, Kecskemét (HU); Ádám István Horváth, Balatonfüred (HU); Máté Pénzes, Budapest (HU); István Lórincz, Budapest (HU); László Végner, Budapest (HU); Zoltán Simon, Oroszlány (HU); Sándor Bátori, Budapest (HU); Zoltán Szónyegi, Budapest (HU); Vajk Horváth, Budapest (HU); and József Répási, Érd (HU)
Assigned to PRINTNET KERESKEDELMI ÉS SZOLGÁLTATÓ KFT., Veresegyház (HU); and EÖTVÖS LORÁND TUDOMÁNYEGYETEM, Budapest (HU)
Filed by PRINTNET KERESKEDELMI ÉS SZOLGÁLTATÓ KFT., Veresegyház (HU); and Eötvös Loránd Tudományegyetem, Budapest (HU)
Filed on Sep. 8, 2023, as Appl. No. 18/464,156.
Application 18/464,156 is a continuation of application No. 18/345,772, filed on Jun. 30, 2023, granted, now 11,845,758, issued on Dec. 19, 2023.
Application 18/345,772 is a continuation of application No. 17/048,206, granted, now 11,746,112, issued on Sep. 5, 2023, previously published as PCT/HU2019/050017, filed on Apr. 18, 2019.
Claims priority of application No. P1800129 (HU), filed on Apr. 18, 2018.
Prior Publication US 2024/0270752 A1, Aug. 15, 2024
This patent is subject to a terminal disclaimer.
Int. Cl. C07D 487/14 (2006.01)
CPC C07D 487/14 (2013.01)
12 Claims
1. A method of treating a condition in a subject in need thereof, comprising administering to the subject a compound that is:
or a pharmaceutically acceptable salt or stereoisomer thereof;
wherein the condition is back pain, muscle spasms, post-stroke spasticity, drug-induced convulsions, or myopathy in skeletal muscle.
