	US 12,421,212 B2
	Substituted benzenecarboxamides as IL-17A modulators
Paul R. Fatheree, San Francisco, CA (US); Martin S. Linsell, South San Francisco, CA (US); John R. Jacobsen, San Mateo, CA (US); Wouter A. Van Der Linden, South San Francisco, CA (US); Timothy J. Church, South San Francisco, CA (US); Claudio Aquino, South San Francisco, CA (US); and Margot G. Paulick, South San Francisco, CA (US)
Assigned to DiCE Alpha, Inc., Indianapolis, IN (US)
Filed by DiCE Alpha, Inc., Indianapolis, IN (US)
Filed on Jan. 27, 2022, as Appl. No. 17/585,974.
Application 17/585,974 is a continuation of application No. 17/118,947, filed on Dec. 11, 2020, granted, now 11,274,094.
Application 17/118,947 is a continuation of application No. PCT/US2020/050924, filed on Sep. 15, 2020.
Application PCT/US2020/050924 is a continuation of application No. 16/783,268, filed on Feb. 6, 2020, granted, now 11,447,468.
Application PCT/US2020/050924 is a continuation of application No. PCT/US2020/016925, filed on Feb. 6, 2020.
Claims priority of provisional application 63/061,719, filed on Aug. 5, 2020.
Claims priority of provisional application 62/901,249, filed on Sep. 16, 2019.
Prior Publication US 2022/0235038 A1, Jul. 28, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 31/167 (2006.01); C07C 233/07 (2006.01); C07D 241/04 (2006.01); C07D 401/12 (2006.01); C07D 403/12 (2006.01); C07D 403/14 (2006.01); C07D 413/12 (2006.01); C07D 455/02 (2006.01); C07D 471/04 (2006.01)

CPC C07D 403/12 (2013.01) [C07D 241/04 (2013.01); C07D 401/12 (2013.01); C07D 403/14 (2013.01); C07D 413/12 (2013.01); C07D 455/02 (2013.01); C07D 471/04 (2013.01)]

10 Claims

1. A compound of the following formula:

or a stereoisomer thereof, or a pharmaceutically acceptable salt of said compound or stereoisomer.

8. A pharmaceutical composition comprising a pharmaceutically acceptable excipient and a compound of the following formula:

or a stereoisomer thereof, or a pharmaceutically acceptable salt of said compound or stereoisomer.