US 12,421,208 B2
Chemical compounds
Jeffrey Wallace Johannes, Wilmington, DE (US); Sudhir Mahadeo Hande, Wilmington, DE (US); Avipsa Ghosh, Wilmington, DE (US); Xiaolan Zheng, Wilmington, DE (US); Martin Packer, Cambridge (GB); and Sebastien Louis Degorce, Cambridge (GB)
Assigned to ASTRAZENECA AB, Södertälje (SE)
Filed by ASTRAZENECA AB, Sodertalje (SE)
Filed on Sep. 14, 2023, as Appl. No. 18/467,185.
Application 18/467,185 is a continuation of application No. 17/354,322, filed on Jun. 22, 2021, granted, now 11,795,158.
Claims priority of provisional application 63/120,351, filed on Dec. 2, 2020.
Claims priority of provisional application 63/044,095, filed on Jun. 25, 2020.
Prior Publication US 2024/0010631 A1, Jan. 11, 2024
This patent is subject to a terminal disclaimer.
Int. Cl. C07D 401/12 (2006.01)
CPC C07D 401/12 (2013.01) 9 Claims
 
1. A compound of Formula I

OG Complex Work Unit Chemistry
wherein:
R1 is independently selected from H, C1-4 alkyl, C3-6 cycloalkyl, C1-4 fluoroalkyl, and C1-4 alkyloxy;
R2 is independently selected from H, halo, C1-4 alkyl, and C1-4 fluoroalkyl; and
R3 is H or C1-4 alkyl;
R4 is halo or C1-4 alkyl,
or a pharmaceutically acceptable salt thereof.