US 12,420,501 B2
Silicone hydrogel lenses with water-rich surfaces
Yongxing Qiu, Suwanee, GA (US); John Dallas Pruitt, Suwanee, GA (US); Sibichen J. Thekveli, Alpharetta, GA (US); Robert Carey Tucker, Johns Creek, GA (US); and Jared Nelson, Buford, GA (US)
Assigned to Alcon Inc., Fribourg (CH)
Filed by Alcon Inc., Fribourg (CH)
Filed on May 23, 2022, as Appl. No. 17/750,518.
Application 17/750,518 is a continuation of application No. 16/925,060, filed on Jul. 9, 2020, granted, now 11,364,695.
Application 16/925,060 is a continuation of application No. 16/582,624, filed on Sep. 25, 2019, granted, now 10,781,340, issued on Sep. 22, 2020.
Application 16/582,624 is a continuation of application No. 16/166,379, filed on Oct. 22, 2018, granted, now 10,513,628, issued on Dec. 24, 2019.
Application 16/166,379 is a continuation of application No. 15/730,773, filed on Oct. 12, 2017, granted, now 10,131,815, issued on Nov. 20, 2018.
Application 15/730,773 is a continuation of application No. 15/202,759, filed on Jul. 6, 2016, granted, now 9,816,009, issued on Nov. 14, 2017.
Application 15/202,759 is a continuation of application No. 14/967,733, filed on Dec. 14, 2015, granted, now 9,411,171, issued on Aug. 9, 2016.
Application 14/967,733 is a continuation of application No. 14/564,660, filed on Dec. 9, 2014, granted, now 9,244,200, issued on Jan. 26, 2016.
Application 14/564,660 is a continuation of application No. 13/900,136, filed on May 22, 2013, granted, now 8,939,577, issued on Jan. 27, 2015.
Application 13/900,136 is a continuation of application No. 13/193,653, filed on Jul. 29, 2011, granted, now 8,480,227, issued on Jul. 9, 2013.
Claims priority of provisional application 61/448,478, filed on Mar. 2, 2011.
Claims priority of provisional application 61/369,102, filed on Jul. 30, 2010.
Prior Publication US 2022/0281190 A1, Sep. 8, 2022
Int. Cl. B29D 11/00 (2006.01); C08G 77/388 (2006.01); C08J 5/00 (2006.01); C08J 7/04 (2020.01); C08L 83/04 (2006.01); C08L 101/14 (2006.01); C09D 5/16 (2006.01); C09D 133/02 (2006.01); C09D 133/14 (2006.01); C09D 133/26 (2006.01); C09D 171/02 (2006.01); C09D 177/06 (2006.01); G02B 1/04 (2006.01); G02B 1/10 (2015.01); G02B 1/18 (2015.01); G02C 7/04 (2006.01)
CPC B29D 11/00067 (2013.01) [C08G 77/388 (2013.01); C08J 5/00 (2013.01); C08J 7/042 (2013.01); C08L 83/04 (2013.01); C08L 101/14 (2013.01); C09D 5/1637 (2013.01); C09D 5/1681 (2013.01); C09D 133/02 (2013.01); C09D 133/14 (2013.01); C09D 133/26 (2013.01); C09D 171/02 (2013.01); C09D 177/06 (2013.01); G02B 1/043 (2013.01); G02B 1/10 (2013.01); G02B 1/18 (2015.01); G02C 7/049 (2013.01); C08J 2383/04 (2013.01); C08J 2383/08 (2013.01); C08J 2433/02 (2013.01); C08J 2433/26 (2013.01); C08J 2487/00 (2013.01); G02C 2202/06 (2013.01); G02C 2202/16 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A hydrated silicone hydrogel contact lens, comprising:
an anterior surface and an opposite posterior surface;
a layered structural configuration from the anterior surface to the posterior surface, wherein the layered structural configuration includes an anterior outer hydrogel layer having a first water content, an inner layer having a second water content, and a posterior outer hydrogel layer having a third water content; and
a water content gradient in the structural configuration from the inner layer to the anterior or posterior outer hydrogel layer in which the first and third water contents are higher than the second water content,
wherein the inner layer is the bulk material of the hydrated silicone hydrogel contact lens and is composed of a silicone hydrogel material which is a copolymerization product of a silicone hydrogel lens formulation comprising (i) at least one hydrophilic vinylic monomer and (ii) at least one polysiloxane-containing vinylic monomer and/or at least one polysiloxane-containing vinylic macromer,
wherein the anterior and posterior outer hydrogel layer independent of each other are composed of a crosslinked polymeric material that is not water-soluble and contains at least 10% by weight of water within its polymer matrix when fully hydrated and that comprises poly (ethylene glycol) chains which are designated as PEG chains,
wherein the hydrated silicone hydrogel contact lens has: an oxygen transmissibility of at least about 40 barrers/mm; an elastic modulus (or Young's Modulus) of from about 0.3 MPa to about 1.8 MPa; and a critical coefficient of friction, designated as CCOF, of 0.046 or less.