US 12,420,024 B2
Drug delivery device with feedback mechanism
Thomas Mark Kemp, Ashwell (GB); and Hugo Revellat, Royston (GB)
Assigned to Sanofi-Aventis Deutschland GMBH, Frankfurt am Main (DE)
Filed by SANOFI-AVENTIS DEUTSCHLAND GMBH, Frankfurt am Main (DE)
Filed on Jan. 17, 2025, as Appl. No. 19/028,896.
Application 19/028,896 is a continuation of application No. 18/968,712, filed on Dec. 4, 2024.
Application 18/968,712 is a continuation of application No. 17/172,602, filed on Feb. 10, 2021, granted, now 12,186,540, issued on Jan. 7, 2025.
Application 17/172,602 is a continuation of application No. 15/578,668, granted, now 10,940,270, issued on Mar. 9, 2021, previously published as PCT/EP2016/062455, filed on Jun. 2, 2016.
Claims priority of application No. 15170590 (EP), filed on Jun. 3, 2015.
Prior Publication US 2025/0161582 A1, May 22, 2025
Int. Cl. A61M 5/315 (2006.01); A61M 5/20 (2006.01); A61M 5/32 (2006.01)
CPC A61M 5/3157 (2013.01) [A61M 5/2033 (2013.01); A61M 5/3245 (2013.01); A61M 2005/208 (2013.01); A61M 2005/3247 (2013.01); A61M 2005/3267 (2013.01); A61M 2205/581 (2013.01); A61M 2205/582 (2013.01)] 29 Claims
OG exemplary drawing
 
1. A method comprising:
axially moving a release member of an autoinjector towards an outer sleeve of the autoinjector, wherein the outer sleeve is at a proximal portion of the autoinjector;
after axially moving the release member towards the outer sleeve, moving a plunger of the autoinjector relative to a case of the autoinjector from (a) a first position in which an inner sleeve of the autoinjector engages a latch on a proximal end of the plunger to hold the plunger in the first position, to (b) a second position in which the inner sleeve has disengaged from the latch of the plunger;
after moving the plunger from the first position into the second position, moving the plunger in a distal direction to a drug delivery position to deliver a medicament from a syringe of the autoinjector;
after moving the plunger into the drug delivery position, axially moving the inner sleeve relative to and within the outer sleeve under a biasing force of a control spring of the autoinjector;
inwardly deflecting a flexible arm of the inner sleeve relative to an inner sleeve body of the inner sleeve as the inner sleeve moves within the outer sleeve, wherein the flexible arm is movable between (i) a deflected position in which the flexible arm engages the outer sleeve and (2) a relaxed position in which the flexible arm extends radially outward relative to the inner sleeve body; and
generating an audible signal or a tactile signal to indicate completion of dispensing of the medicament when the flexible arm of the inner sleeve engages the outer sleeve,
wherein the autoinjector is configured such that the outer sleeve and the plunger rotate relative to each other before the plunger moves into the drug delivery position.