US 12,419,956 B2
Controlled drug release system of photoresponsive nanocarriers, methods of making and using thereof
Weiping Wang, Hong Kong (CN); and Kaiqi Long, Hong Kong (CN)
Assigned to THE UNIVERSITY OF HONG KONG, Hong Kong (CN)
Appl. No. 17/904,833
Filed by THE UNIVERSITY OF HONG KONG, Hong Kong (CN)
PCT Filed Mar. 17, 2021, PCT No. PCT/CN2021/081262
§ 371(c)(1), (2) Date Aug. 23, 2022,
PCT Pub. No. WO2021/213089, PCT Pub. Date Oct. 28, 2021.
Claims priority of provisional application 63/014,954, filed on Apr. 24, 2020.
Prior Publication US 2023/0124487 A1, Apr. 20, 2023
Int. Cl. A61K 47/22 (2006.01); A61K 9/51 (2006.01); A61K 31/337 (2006.01); A61K 31/704 (2006.01); A61K 31/7068 (2006.01); A61K 41/00 (2020.01); A61N 5/06 (2006.01); A61P 27/16 (2006.01); A61P 35/00 (2006.01); C07D 311/58 (2006.01)
CPC A61K 41/0042 (2013.01) [A61K 9/5123 (2013.01); A61K 31/337 (2013.01); A61K 31/704 (2013.01); A61K 31/7068 (2013.01); A61N 5/062 (2013.01); A61P 27/16 (2018.01); A61P 35/00 (2018.01); C07D 311/58 (2013.01); A61N 2005/0651 (2013.01); A61N 2005/0659 (2013.01); A61N 2005/0663 (2013.01)] 22 Claims
 
1. A drug delivery system comprising: a nanocarrier and a pharmaceutical agent, wherein the nanocarrier comprises (DEAdcCM)3-TAEA (DTAEA) having the formula:

OG Complex Work Unit Chemistry