US 12,419,939 B2
Vaccine and methods for detecting and preventing filariasis
Ramaswamy Kalyanasundaram, Rockford, IL (US)
Assigned to The Board of Trustees of the University of Illinois, Urbana, IL (US)
Appl. No. 17/798,189
Filed by THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS, Urbana, IL (US)
PCT Filed Feb. 12, 2021, PCT No. PCT/US2021/017813
§ 371(c)(1), (2) Date Aug. 8, 2022,
PCT Pub. No. WO2021/163448, PCT Pub. Date Aug. 19, 2021.
Application 17/798,189 is a continuation in part of application No. 16/790,277, filed on Feb. 13, 2020, granted, now 11,370,814.
Prior Publication US 2023/0089516 A1, Mar. 23, 2023
Int. Cl. A61K 39/00 (2006.01); A61P 33/10 (2006.01)
CPC A61K 39/0003 (2013.01) [A61P 33/10 (2018.01); A61K 2039/53 (2013.01); A61K 2039/552 (2013.01); A61K 2039/70 (2013.01)] 12 Claims
 
1. A multivalent immunogenic composition comprising an Abundant Larval Transcript antigen comprising SEQ ID NO: 122, a Small heat shock protein (HSP) 12.6 antigen comprising SEQ ID NO:81, and a Thioredoxin Peroxidase 2 antigen comprising SEQ ID NO: 83, in combination with two or more adjuvants.