US 12,419,823 B2
Antimicrobial composition
Ying Zhang, Woodbury, MN (US); Robert A. Asmus, Hudson, WI (US); Zhicheng Tian, Woodbury, MN (US); Kheng Vang, St. Paul, MN (US); James P. Dizio, St. Paul, MN (US); Patrick J. Parks, Mendota Heights, MN (US); and Brian E. Spiewak, Inver Grove Heights, MN (US)
Assigned to Solventum Intellectual Properties Company, Maplewood, MN (US)
Appl. No. 17/600,010
Filed by Solventum Intellectual Properties Company, Maplewood, MN (US)
PCT Filed Mar. 26, 2020, PCT No. PCT/IB2020/052891
§ 371(c)(1), (2) Date Sep. 29, 2021,
PCT Pub. No. WO2020/201945, PCT Pub. Date Oct. 8, 2020.
Claims priority of provisional application 62/827,281, filed on Apr. 1, 2019.
Prior Publication US 2022/0105018 A1, Apr. 7, 2022
Int. Cl. A61K 8/49 (2006.01); A61K 8/34 (2006.01); A61K 8/37 (2006.01); A61Q 17/00 (2006.01); A61K 8/41 (2006.01)
CPC A61K 8/4926 (2013.01) [A61K 8/342 (2013.01); A61K 8/345 (2013.01); A61K 8/375 (2013.01); A61Q 17/005 (2013.01)] 19 Claims
 
1. An antimicrobial composition comprising:
60 wt. % to 99.4 wt. % solubilizer, the solubilizer selected from glyceryl monoisostearate, glyceryl monooleate, decagylcerol hexaoleate, decagylcerol decaoleate, and a combination thereof;
0.1 wt. % to 10 wt. % antimicrobial agent, the antimicrobial agent selected from octenidine dihydrochloride, octenidine gluconate, octenidine sulfate, octenidine acetate, and a combination thereof; and
0.1 wt. % to 15 wt. % cidatrope, the cidatrope selected from diisopropyl adipate, dibutyl sebacate, triethyl citrate, acetyltributyl citrate, trioctyldodecyl citrate, PPG-10 butanediol, and a combination thereof,
wherein the composition is substantially free of water and a C2-C5 alcohol.