US 12,419,687 B2
Nasal implant design method of manufacturing patient-customized nasal implant
Eun Hyun Bae, Seoul (KR); and Seo Won Yang, Seoul (KR)
Assigned to BISTOOL INC., Seoul (KR)
Filed by BISTOOL INC., Seoul (KR)
Filed on Aug. 4, 2021, as Appl. No. 17/393,786.
Claims priority of application No. 10-2020-0098629 (KR), filed on Aug. 6, 2020; and application No. 10-2020-0140187 (KR), filed on Oct. 27, 2020.
Prior Publication US 2022/0039867 A1, Feb. 10, 2022
Int. Cl. A61B 34/10 (2016.01); G06N 20/00 (2019.01)
CPC A61B 34/10 (2016.02) [G06N 20/00 (2019.01); A61B 2034/104 (2016.02); A61B 2034/105 (2016.02); A61B 2034/108 (2016.02)] 11 Claims
OG exemplary drawing
 
1. A nasal implant design method of manufacturing a patient-customized nasal implant, the nasal implant design method comprising:
(a) acquiring a medical image of a patient's nasal portion wherein the medical image is a computed tomography (CT) image resulting from low-dose radiation exposure or a cone beam computed tomography (CBCT) image resulting from low-dose radiation exposure;
(b) automatically realizing a three-dimensional volume rendering image, including skin, bones, and cartilage of a nasal portion, from the CT image resulting from low-dose radiation exposure or a CBCT image resulting from low-dose radiation exposure of the patient's nasal portion on the basis of nasal cartilage data learned through artificial intelligence without performing a triangle mesh data operation through segmentation, wherein said automatic realizing comprises predicting the nasal cartilage from the medical image of the patient's nasal portion on the basis of the nasal cartilage data learned through a deep learning scheme using medical images resulting from high-dose radiation exposure from which the nasal cartilage is visible;
(c) simulating the nasal cartilage with the three-dimensional volume rendering image;
(d) stably nesting a nasal implant selected from a virtual nasal implant model database on the simulated nasal cartilage and the nasal bones;
(e) simulating the stably nested nasal implant and designing a patient-customized nasal implant,
(f) cutting an arbitrary surface of a patient-customized nasal cartilage from the patient-customized nasal implant and verifying whether or not the patient-customized nasal cartilage is brought into contact with the simulated nasal cartilage and the nasal bones; and
(g) automatically computing and displaying a change in a height of a skin surface of the nasal portion with respect to the patient-customized nasal implant.