US 12,419,539 B2
Passive, proportional measurement of oxygen and carbon dioxide consumption for assessment of metabolic parameters
Holly McClung, Westborough, MA (US); Reed Wasson Hoyt, Cambridge, MA (US); Lawrence M Candell, Arlington, MA (US); Joseph M. Mahan, Beverly, MA (US); Gary A Shaw, Westford, MA (US); Andrew M Siegel, Arlington, MA (US); Robert Linton Standley, Acton, MA (US); and Kyle Thompson, Boulder, CO (US)
Assigned to Massachusetts Institute of Technology, Cambridge, MA (US); and The Government of the United States, as Represented by the Secretary of the Army, Fort Detrick, MD (US)
Filed by Massachusetts Institute of Technology, Cambridge, MA (US)
Filed on Aug. 11, 2022, as Appl. No. 17/819,054.
Application 17/819,054 is a continuation of application No. 16/414,003, filed on May 16, 2019, granted, now 11,464,426.
Claims priority of provisional application 62/672,443, filed on May 16, 2018.
Prior Publication US 2023/0089871 A1, Mar. 23, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. A61B 5/097 (2006.01); A61B 5/083 (2006.01); A61B 5/087 (2006.01); A61M 16/08 (2006.01)
CPC A61B 5/097 (2013.01) [A61B 5/0833 (2013.01); A61B 5/0836 (2013.01); A61B 5/087 (2013.01); A61B 2562/06 (2013.01); A61M 16/0808 (2013.01)] 13 Claims
OG exemplary drawing
 
1. A flow-rate proportional passive side-stream sampling system comprising:
a flow tube, defining an inner lumen extending from an inlet of the flow tube to an outlet of the flow tube, the inner lumen having a constriction between the inlet and the outlet, the flow tube configured to receive an exhaled breath from a person at the inlet, convey the exhaled breath from the inlet to the outlet via the inner lumen, and convey an inhalation from the outlet to the inlet and to the person via the inner lumen, wherein the flow tube includes a bend between the inlet and the outlet;
a first port disposed on the flow tube between the inlet of the flow tube and the outlet and in fluid communication with the inner lumen, the first port arranged to receive a fraction of the exhaled breath in proportion to an instantaneous flow rate of the exhaled breath; and
a mixing chamber, in fluid communication with the first port to receive the fraction of the exhaled breath.