US 12,092,521 B2
Method for quantifying solutions comprised of multiple analytes
Mark Selker, Los Altos Hills, CA (US); and Barbara Paldus, Atherton, CA (US)
Assigned to Finesse Solutions, Inc., Santa Clara, CA (US)
Filed by Finesse Solutions, Inc., Santa Clara, CA (US)
Filed on Mar. 3, 2022, as Appl. No. 17/685,595.
Application 17/685,595 is a continuation of application No. 17/012,289, filed on Sep. 4, 2020, granted, now 11,274,967.
Application 17/012,289 is a continuation of application No. 16/121,734, filed on Sep. 5, 2018, granted, now 10,768,050, issued on Sep. 8, 2020.
Application 16/121,734 is a continuation of application No. 13/506,585, filed on Apr. 30, 2012, granted, now 10,101,209, issued on Oct. 16, 2018.
Prior Publication US 2022/0187128 A1, Jun. 16, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. G01J 3/44 (2006.01); G01J 3/02 (2006.01); G01N 21/65 (2006.01); G02B 6/02 (2006.01)
CPC G01J 3/44 (2013.01) [G01J 3/0218 (2013.01); G01N 21/65 (2013.01); G02B 6/02385 (2013.01); G01N 2201/08 (2013.01); G01N 2201/129 (2013.01); G02B 6/02328 (2013.01)] 13 Claims
OG exemplary drawing
 
1. A method of determining the identity and concentration of a target analyte present in a biological sample, the method comprising:
introducing a first target analyte into a hollow core of an optical fiber;
introducing a first reference calibrant into the hollow core of the optical fiber;
transmitting light from a laser light source through the hollow core of the optical fiber and the first target analyte to generate a first Raman anti-Stokes analyte emission corresponding to the first target analyte;
receiving the first Raman anti-Stokes analyte emission at a spectral analysis system optically coupled to the optical fiber; and
deriving Raman anti-Stokes spectral peaks or spectra of the first target analyte at the spectral analysis system based on the first Raman anti-Stokes analyte emission.