US 12,091,652 B2
Ammonia-oxidizing Nitrosomonas eutropha strain D23
David R. Whitlock, Cambridge, MA (US); Spiros Jamas, Cambridge, MA (US); Larry Weiss, San Francisco, CA (US); and Ioannis Gryllos, Brookline, MA (US)
Assigned to AOBIOME LLC, Cambridge, MA (US)
Filed by AOBIOME LLC, Cambridge, MA (US)
Filed on Nov. 23, 2020, as Appl. No. 17/101,871.
Application 17/101,871 is a continuation of application No. 16/856,789, filed on Apr. 23, 2020, abandoned.
Application 16/856,789 is a continuation of application No. 16/596,694, filed on Oct. 8, 2019, abandoned.
Application 16/596,694 is a continuation of application No. 15/304,151, abandoned, previously published as PCT/US2015/025909, filed on Apr. 15, 2015.
Claims priority of provisional application 62/053,588, filed on Sep. 22, 2014.
Claims priority of provisional application 62/012,811, filed on Jun. 16, 2014.
Claims priority of provisional application 62/002,084, filed on May 22, 2014.
Claims priority of application No. 20140100217 (GR), filed on Apr. 15, 2014; and application No. 20150100115 (GR), filed on Mar. 13, 2015.
Prior Publication US 2022/0002662 A1, Jan. 6, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. C12N 1/20 (2006.01); A61K 8/99 (2017.01); A61K 9/00 (2006.01); A61K 35/74 (2015.01); A61K 35/744 (2015.01); A61K 35/745 (2015.01); A61K 35/747 (2015.01); A61K 48/00 (2006.01); A61L 15/36 (2006.01); A61Q 15/00 (2006.01); A61Q 17/04 (2006.01); A61Q 19/00 (2006.01); C07K 14/195 (2006.01); C12N 1/00 (2006.01); C12Q 1/02 (2006.01); C12Q 1/689 (2018.01); A61Q 19/02 (2006.01); A61Q 19/04 (2006.01); C12R 1/01 (2006.01)
CPC C12N 1/20 (2013.01) [A61K 8/99 (2013.01); A61K 9/0014 (2013.01); A61K 35/74 (2013.01); A61K 35/744 (2013.01); A61K 35/745 (2013.01); A61K 35/747 (2013.01); A61K 48/00 (2013.01); A61L 15/36 (2013.01); A61Q 15/00 (2013.01); A61Q 17/04 (2013.01); A61Q 19/00 (2013.01); C07K 14/195 (2013.01); C12N 1/00 (2013.01); C12N 1/205 (2021.05); C12Q 1/02 (2013.01); C12Q 1/689 (2013.01); A61Q 19/02 (2013.01); A61Q 19/04 (2013.01); C12R 2001/01 (2021.05)] 12 Claims
 
1. A Nitrosomonas eutropha bacterium having American Type Culture Collection designation number PTA-121157 or having a genomic DNA comprising the nucleotide sequence of SEQ ID NO: 1 or the full-length complementary nucleotide sequence of SEQ ID NO: 1.