US 12,090,250 B2
Demineralized bone fibers and preparation thereof
Silvia Chen, Kendall Park, VA (US); Grant Cleavenger, Virginia Beach, VA (US); Dennis Phelps, Chesapeake, VA (US); Evans Wralstad, Virginia Beach, VA (US); Breanne Gjurich, Norfolk, VA (US); Austin Johnson, Virginia Beach, VA (US); Alana Sampson, Virginia Beach, VA (US); Adam Entsminger, Virginia Beach, VA (US); and Jingsong Chen, Virginia Beach, VA (US)
Assigned to LifeNet Health, Virginia Beach, VA (US)
Filed by LifeNet Health, Virginia Beach, VA (US)
Filed on May 17, 2021, as Appl. No. 17/321,904.
Application 17/321,904 is a continuation of application No. 16/309,505, previously published as PCT/US2017/037265, filed on Jun. 13, 2017.
Claims priority of provisional application 62/349,509, filed on Jun. 13, 2016.
Claims priority of provisional application 62/351,501, filed on Jun. 17, 2016.
Prior Publication US 2021/0268147 A1, Sep. 2, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. A61L 27/36 (2006.01); A61K 35/32 (2015.01)
CPC A61L 27/3608 (2013.01) [A61K 35/32 (2013.01); A61L 27/365 (2013.01); A61L 27/3687 (2013.01); A61L 2430/02 (2013.01)] 35 Claims
OG exemplary drawing
 
1. A method for preparing a demineralized bone graft, wherein the demineralized bone graft has a residual calcium content of less than 6 wt % based on the dry weight of the demineralized bone graft, comprising subjecting a non-demineralized bone graft to a single incubation in an acid solution for no more than 300 seconds, wherein the acid solution has a pH of 0-4.