US 12,089,593 B2
Compositions and methods for treating and preventing dust mite infestation
Jean Davin Amick, Lexington, KY (US); and Bryan N. Julien, Lexington, KY (US)
Assigned to DANSTAR FERMENT AG, Zug (CH)
Appl. No. 16/086,494
Filed by EVOLVA SA, Reinach (CH)
PCT Filed Mar. 24, 2017, PCT No. PCT/EP2017/057124
§ 371(c)(1), (2) Date Sep. 19, 2018,
PCT Pub. No. WO2017/162877, PCT Pub. Date Sep. 28, 2017.
Claims priority of provisional application 62/341,321, filed on May 25, 2016.
Claims priority of provisional application 62/313,001, filed on Mar. 24, 2016.
Prior Publication US 2019/0090482 A1, Mar. 28, 2019
This patent is subject to a terminal disclaimer.
Int. Cl. A01N 35/06 (2006.01); A61L 2/10 (2006.01); A61L 2/18 (2006.01); B08B 5/04 (2006.01)
CPC A01N 35/06 (2013.01) [A61L 2/10 (2013.01); A61L 2/18 (2013.01); B08B 5/04 (2013.01)] 18 Claims
 
1. A method of treating or preventing a dust mite infestation comprising:
(a) providing a nootkatone-containing composition, wherein the nootkatone is nootkatone ex valencene, wherein the nootkatone ex valencene is limonene-free and bergapten-free, and wherein the nootkatone-containing composition is limonene-free and bergapten-free;
(b) optionally reducing the concentration of the composition to a working concentration with a carrier;
(c) applying an effective amount of the composition to a surface; and
(d) killing or repelling dust mites on the surface,
wherein the composition has a reduced risk for causing allergy or asthma symptoms or breathing difficulties if inhaled compared to a composition comprising nootkatone that is neither limonene-free nor bergapten-free, and
wherein the dust mite infestation comprises dust mites of the genus Dermatophagoides.