| CPC G16H 10/20 (2018.01) | 18 Claims |

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1. A method of managing access to data associated with trials for digital therapeutics on participants, comprising:
receiving, by a server, from a user device, a request to define a plurality of parameters for at least one trial, the plurality of parameters identifying at least one of a digital therapeutic, a plurality of phases, or a respective endpoint for each of the plurality of phases;
establishing, by the server, a data lake comprising a data storage to store a plurality of datasets in at least one of a structured format or an unstructured format for the at least one trial in accordance with the plurality of parameters;
maintaining, by the server, for multiple digital therapeutics, the data lake for a plurality of phases associated with a trial for a digital therapeutic provided by a digital therapeutic application to a plurality of participants, the plurality of phases including (a) a pre-trial phase prior to commencing the trial for the digital therapeutic, (b) a trial phase during the trial, and (c) a post-trial phase subsequent to completion of the trial for the digital therapeutic, wherein the data lake maintains the data of the plurality of phases in a centralized manner, the data lake comprising:
(i) a plurality of datasets from the pre-trial phase,
(ii) a plurality of datasets from the trial phase, and
(iii) a plurality of datasets from the post-trial phase;
receiving, by the server, from the user device, an additional request associated with a participant or group of participants, an endpoint, and a phase of the plurality of phases for which the plurality of datasets is to be accessed;
selecting, by the server, a corresponding portion of the plurality of datasets based on the additional request, wherein the corresponding portion is selected by identifying linked data linked by an association between a plurality of trials; and
providing, by the server, to the user device, the corresponding portion of the plurality of datasets in the data lake.
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