US 12,414,913 B1
Implantable device having piston displacement monitoring
Raju S. Dave, Gaithersburg, MD (US); Xing Su, Santa Clara, CA (US); Himanshu Verma, McLean, VA (US); and Palamadai Venkatraman, Edison, NJ (US)
Assigned to MantaMedTech LLC
Filed by MantaMedTech LLC, Newark, DE (US)
Filed on Dec. 31, 2024, as Appl. No. 19/006,316.
Int. Cl. A61K 9/00 (2006.01); A61M 5/168 (2006.01)
CPC A61K 9/0004 (2013.01) [A61M 5/16813 (2013.01); A61M 2205/18 (2013.01); A61M 2205/3306 (2013.01); A61M 2205/3317 (2013.01); A61M 2205/3344 (2013.01); A61M 2205/3375 (2013.01)] 20 Claims
OG exemplary drawing
 
1. An active implantable medical device (AIMD), comprising:
a permeability module that allows ingress flow of a fluid to an osmotic agent chamber and generates osmotic pressure;
a piston that moves longitudinally within the active implantable medical device (AIMD) in response to the osmotic pressure;
a drug chamber that comprises a drug and a valve module to allow one-way flow of the drug from the drug chamber to outside the active implantable medical device (AIMD);
a sensor module configured to measure a displacement of the piston and provide displacement data during real-time operation of the active implantable medical device (AIMD);
an electronic module that communicates a signal to the valve module to control the valve module and regulate the one-way flow of the drug based on the displacement data of the piston such that a dose-to-dose drug ejection variation from the active implantable medical device (AIMD) is less than ±25% by volume of a predetermined volume; and
a machine learning, model configured to cause the active implantable medical device (AIMD) to trigger an alert in case dosing is outside threshold limits.