US 12,414,906 B2
Compositions and methods for treating hot flashes
Connie Michelle Dunaway, West Chester, OH (US); Samantha Chen-Yee Wang, Cincinnati, OH (US); Mary Jane Watson, Cincinnati, OH (US); Matthew Lawrence Lynch, Mariemont, OH (US); Jamie Lynn Dria, Deerfield Township, OH (US); Brandon Philip Illie, Felicity, OH (US); Taotao Zhu, West Chester, OH (US); Dorothy Angela Hall, Blanchester, OH (US); and Beth Ann Schubert, Maineville, OH (US)
Assigned to The Procter & Gamble Company, Cincinnati, OH (US)
Filed by The Procter & Gamble Company, Cincinnati, OH (US)
Filed on Oct. 10, 2022, as Appl. No. 17/962,763.
Application 17/962,763 is a continuation of application No. PCT/US2021/026359, filed on Apr. 8, 2021.
Claims priority of provisional application 63/007,965, filed on Apr. 10, 2020.
Claims priority of provisional application 63/007,973, filed on Apr. 10, 2020.
Claims priority of provisional application 63/007,967, filed on Apr. 10, 2020.
Claims priority of provisional application 63/007,972, filed on Apr. 10, 2020.
Prior Publication US 2023/0050077 A1, Feb. 16, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 8/49 (2006.01); A61K 8/02 (2006.01); A61K 8/20 (2006.01); A61K 8/34 (2006.01); A61K 8/36 (2006.01); A61K 8/37 (2006.01); A61K 8/73 (2006.01); A61K 8/92 (2006.01); A61K 31/16 (2006.01); A61K 31/20 (2006.01); A61K 31/22 (2006.01); A61K 31/23 (2006.01); A61K 45/06 (2006.01); A61P 43/00 (2006.01); A61Q 19/00 (2006.01)
CPC A61K 8/4973 (2013.01) [A61K 8/34 (2013.01); A61K 8/37 (2013.01); A61K 31/23 (2013.01); A61P 43/00 (2018.01); A61Q 19/00 (2013.01); A61K 2800/10 (2013.01)] 18 Claims
OG exemplary drawing
 
1. A personal care composition comprising:
i.) from about 1% to about 12% by weight of a salt of a fatty acid containing from 13 to about 20 carbon atoms,
ii.) from about 70% to about 99.5% by weight water,
iii.) from 0.5% to about 15% by weight of an alcohol selected from the group consisting of methanol, ethanol, propanol, isopropanol, and mixtures thereof, and
iv.) from about 0.1% to about 25% by weight of a cooling sensate;
wherein:
the salt of a fatty acid functions as a crystallizing agent to form a crystalline mesh with voids;
the voids comprise aqueous solution; and
the aqueous solution is expressed when the personal care composition is compressed above a critical stress;
wherein the personal care composition has a liquid expression from about 300 J m-3 to about 9,000 J m-3, as determined by the AQUEOUS SOLUTION EXPRESSION TEST METHOD at room temperature (25±3° C.); and
wherein the composition has a firmness between about 0.1 N to about 50.0 N, as determined by the FIRMNESS TEST METHOD at room temperature (25±3° C.).