US 12,085,560 B2
Biochemical reaction substrate with sloping flow passage to absorber and analyzer therefore
Kenji Uemura, Misato (JP); Norio Tanimoto, Misato (JP); Mai Egami, Misato (JP); Takahiro Mataki, Tokyo (JP); Yumi Konishi, Misato (JP); Motoe Shimizu, Ueda (JP); Shigenori Takahashi, Ueda (JP); and Koji Sakaguchi, Ueda (JP)
Assigned to NIPPON CHEMIPHAR CO., LTD., Tokyo (JP)
Appl. No. 16/966,765
Filed by NIPPON CHEMIPHAR CO., LTD., Tokyo (JP); and UEDA JAPAN RADIO CO., LTD., Ueda (JP)
PCT Filed Feb. 1, 2019, PCT No. PCT/JP2019/003559
§ 371(c)(1), (2) Date Jul. 31, 2020,
PCT Pub. No. WO2019/151468, PCT Pub. Date Aug. 8, 2019.
Claims priority of application No. 2018-017628 (JP), filed on Feb. 2, 2018; and application No. 2018-186756 (JP), filed on Oct. 1, 2018.
Prior Publication US 2021/0364503 A1, Nov. 25, 2021
Int. Cl. G01N 33/543 (2006.01); B01L 3/00 (2006.01); B01L 9/00 (2006.01); G01N 35/00 (2006.01); G01N 35/02 (2006.01)
CPC G01N 33/543 (2013.01) [B01L 3/502 (2013.01); B01L 9/527 (2013.01); G01N 35/00732 (2013.01); G01N 35/021 (2013.01)] 12 Claims
OG exemplary drawing
 
1. A biochemical reaction substrate, comprising:
a reaction plate; an absorber; a reaction plate storing portion for storing the reaction plate; an absorber storing portion for storing the absorber; a storage container having a wall; and a cover assembled to the storage container so as to cover at least a part of the reaction plate and the absorber stored in the storage container, wherein
the reaction plate includes a reaction area in which a specific binding substance that specifically reacts with a substance to be tested in a specimen is immobilized, and a flow passage that connects the absorber and the reaction area, and wherein
the cover includes an injection hole for injecting a specimen or the like into the reaction plate,
wherein the reaction plate storing portion and the absorber storing portion are in the storage container, and
wherein the flow passage has a slope formed in such a way to climb up from the reaction area.
 
5. An analyzer for analyzing reaction between a specimen and a reagent, the analyzer comprising:
an installation area comprising therein a reagent cartridge, for storing the specimen and the reagent, and a biochemical reaction substrate for dispensing the specimen and the reagent;
a dispensing area where the specimen and/or the reagent is dispensed into the biochemical reaction substrate;
a stirring area where the dispensed specimen and/or reagent is stirred and mixed;
a drainage area where the stirred and mixed specimen and reagent are drained;
a detection area where reaction between the specimen and the reagent in the biochemical reaction substrate is detected, wherein the installation area, the dispensing area, the stirring area, the drainage area and the detection area are, in any order, arranged on a same straight line;
a guide device disposed along the same straight line and comprising a drive source; and
a moving table guided, by the drive source along the guide device, among each the installation area, the dispensing area, the stirring area, the drainage area and the detection area.