	US 12,084,674 B2
	Methods and compositions for a HIV based delivery system
Saveez Saffarian, Salt Lake City, UT (US); and Mourad Bendjennat, Salt Lake City, UT (US)
Assigned to UNIVERSITY OF UTAH RESEARCH FOUNDATION, Salt Lake City, UT (US)
Filed by University of Utah Research Foundation, Salt Lake City, UT (US)
Filed on Oct. 7, 2020, as Appl. No. 17/065,101.
Claims priority of provisional application 62/911,812, filed on Oct. 7, 2019.
Prior Publication US 2021/0102221 A1, Apr. 8, 2021
Int. Cl. C12N 15/86 (2006.01); C12N 15/113 (2010.01); C12Q 1/70 (2006.01)

CPC C12N 15/86 (2013.01) [C12N 15/113 (2013.01); C12Q 1/703 (2013.01); C12N 2310/14 (2013.01); C12N 2740/16022 (2013.01); C12N 2740/16111 (2013.01); C12N 2740/16222 (2013.01)]

21 Claims

1. A nucleic acid construct comprising a nucleic acid sequence encoding a modified HIV Gag polypeptide, wherein the modified HIV Gag polypeptide comprises from the N terminus to C-terminus a matrix domain (MA), capsid (CA) domain, SP1 region, nucleocapsid (NC) domain, exogenous peptide, SP2 region, and p6 domain.