	US 12,084,665 B2
	Recombinant acid-resistant yeast in which alcohol production is inhibited and method for producing lactic acid by using same
Jae Yeon Park, Daejeon (KR); Tae Young Lee, Daejeon (KR); and Ki Sung Lee, Daejeon (KR)
Assigned to SK Innovation Co., Ltd., Seoul (KR)
Appl. No. 17/276,306
Filed by SK INNOVATION CO., LTD., Seoul (KR)
PCT Filed Sep. 23, 2019, PCT No. PCT/KR2019/012326 § 371(c)(1), (2) Date Mar. 18, 2021, PCT Pub. No. WO2020/075986, PCT Pub. Date Jun. 16, 2020.
Claims priority of application No. 10-2018-0119721 (KR), filed on Oct. 8, 2018.
Prior Publication US 2022/0056459 A1, Feb. 24, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. C12N 1/16 (2006.01); C12N 9/04 (2006.01); C12N 9/88 (2006.01); C12N 15/81 (2006.01); C12P 7/56 (2006.01)

CPC C12N 15/81 (2013.01) [C12N 1/165 (2021.05); C12N 9/0006 (2013.01); C12N 9/88 (2013.01); C12P 7/56 (2013.01); C12Y 101/01027 (2013.01); C12Y 401/01001 (2013.01)]

8 Claims

1. A recombinant acid-tolerant yeast strain having lactic acid-producing ability and genetically engineered from the yeast strain deposited under accession number KCTC13508BP, wherein a pyruvate decarboxylase-encoding gene has been deleted or attenuated from the deposited yeast strain and a lactate dehydrogenase-encoding gene has been introduced into the deposited yeast strain.