US 12,084,479 B2
Modified antimicrobial peptide derived from an arginine-rich domain
Chiaho Shih, Taipei (TW); Heng-Li Chen, Taipei (TW); and Pei-Yi Su, Taipei (TW)
Assigned to Academia Sinica, Taipei (TW)
Filed by Academia Sinica, Taipei (TW)
Filed on Jul. 17, 2020, as Appl. No. 16/932,372.
Application 16/932,372 is a continuation of application No. 16/303,464, abandoned, previously published as PCT/US2017/034489, filed on May 25, 2017.
Claims priority of provisional application 62/342,415, filed on May 27, 2016.
Prior Publication US 2021/0101939 A1, Apr. 8, 2021
Int. Cl. C07K 14/005 (2006.01); A01N 37/46 (2006.01); A01N 63/50 (2020.01); A61K 38/00 (2006.01); A61P 31/04 (2006.01); C07K 7/08 (2006.01)
CPC C07K 14/005 (2013.01) [A01N 37/46 (2013.01); A01N 63/50 (2020.01); A61P 31/04 (2018.01); C07K 7/08 (2013.01); A61K 38/00 (2013.01); C12N 2730/10122 (2013.01); C12N 2730/10133 (2013.01)] 21 Claims
 
1. An antimicrobial peptide, consisting of RRRGRSPRRRTPSPRRRRSQSPRRRRSC (SEQ ID NO: 7) or RRRGRPRRRPPRRRRQPRRRRC (SEQ ID NO: 9); optionally, at least one of the arginine residues in the peptide is D-arginine.