US 12,083,736 B2
Two-phase 3D printing methods of forming biocompatible structures with immiscible liquids
Daniel Backman, Bedford, NH (US); Mohammadali Safavieh, Nashua, NH (US); Aman Kaur, Manchester, NH (US); Derek Morris, Bedford, NH (US); and Luis M. Alvarez, Lexington, MA (US)
Assigned to Lung Biotechnology PBC, Silver Spring, MD (US)
Filed by Lung Biotechnology PBC, Silver Spring, MD (US)
Filed on Oct. 21, 2022, as Appl. No. 17/971,168.
Claims priority of provisional application 63/271,670, filed on Oct. 25, 2021.
Prior Publication US 2023/0131073 A1, Apr. 27, 2023
Int. Cl. B29C 64/124 (2017.01); B29K 105/00 (2006.01); B33Y 10/00 (2015.01); B33Y 70/00 (2020.01)
CPC B29C 64/124 (2017.08) [B33Y 10/00 (2014.12); B29K 2105/0061 (2013.01); B29K 2105/0085 (2013.01); B29K 2995/0093 (2013.01); B33Y 70/00 (2014.12)] 18 Claims
OG exemplary drawing
 
1. A method of printing a hydrogel scaffold comprising:
providing a container containing an ink and a liquid that is immiscible with the ink,
adding the liquid that is immiscible with the ink to replace at least a portion of the ink consumed or otherwise lost during the printing;
applying light from a light source to the ink to form a portion of the hydrogel scaffold; and
applying light from a light source one or more additional times to produce one or more additional portions of the hydrogel scaffold.