US 12,083,179 B2
Colon cleansing compositions and method of use
Lucy Clayton, Uxbridge (GB); Alasdair Cockett, Uxbridge (GB); Mark Christodoulou, Uxbridge (GB); Ian Davidson, Uxbridge (GB); Lynn Farrag, Uxbridge (GB); Marc Halphen, London (GB); Leighton Jones, Uxbridge (GB); Vanik Petrossian, Woburn, MA (US); Peter Stein, Amsterdam Zuid-Oost (NL); David Tisi, Woburn, MA (US); Alex Ungar, Wigton (GB); and Jeffrey Worthington, Woburn, MA (US)
Assigned to NORGINE BV, Amsterdam (NL)
Filed by NORGINE BV, Amsterdam (NL)
Filed on Jul. 23, 2021, as Appl. No. 17/384,227.
Application 17/384,227 is a continuation of application No. 16/028,819, filed on Jul. 6, 2018.
Application 16/028,819 is a continuation of application No. 15/454,132, filed on Mar. 9, 2017, granted, now 10,016,504, issued on Jul. 10, 2018.
Application 15/454,132 is a continuation of application No. 15/141,054, filed on Apr. 28, 2016, granted, now 9,707,297, issued on Jul. 18, 2017.
Application 15/141,054 is a continuation of application No. 14/657,495, filed on Mar. 13, 2015, granted, now 9,326,969, issued on May 3, 2016.
Application 14/657,495 is a continuation of application No. 14/223,127, filed on Mar. 24, 2014, granted, now 8,999,313, issued on Apr. 7, 2015.
Application 14/223,127 is a continuation of application No. PCT/EP2013/068738, filed on Sep. 10, 2013.
Claims priority of provisional application 61/787,366, filed on Mar. 15, 2013.
Claims priority of provisional application 61/699,488, filed on Sep. 11, 2012.
Prior Publication US 2021/0346503 A1, Nov. 11, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 47/26 (2006.01); A61K 9/00 (2006.01); A61K 9/08 (2006.01); A61K 31/047 (2006.01); A61K 31/375 (2006.01); A61K 31/765 (2006.01); A61K 31/77 (2006.01); A61K 33/04 (2006.01); A61K 33/14 (2006.01); A61K 47/02 (2006.01); A61K 47/10 (2017.01); A61K 47/12 (2006.01)
CPC A61K 47/26 (2013.01) [A61K 9/0053 (2013.01); A61K 9/0095 (2013.01); A61K 9/08 (2013.01); A61K 31/047 (2013.01); A61K 31/375 (2013.01); A61K 31/765 (2013.01); A61K 31/77 (2013.01); A61K 33/04 (2013.01); A61K 33/14 (2013.01); A61K 47/02 (2013.01); A61K 47/10 (2013.01); A61K 47/12 (2013.01)] 20 Claims
 
1. A colon cleansing solution comprising:
(i) 175 to 220 g per litre PEG having an average molecular weight of 2500 to 4500 Da;
(ii) 15 to 20 g per litre of one or more alkali metal sulphates, alkaline earth metal sulphates or a mixture thereof;
(iii) 3.0 to 5.0 g per litre sodium chloride, and 1.5 to 2.5 g per litre potassium chloride;
(iv) optionally one or more flavouring agents; and
(v) optionally one or more sweeteners,
wherein the solution has a volume of 400-600 ml.