	US 12,083,156 B1
	Extracts derived from laser-irradiated rhizome of curcuma longa having enhanced antimicrobial activity
Munirah Fahad Aldayel, Al-Ahsa (SA)
Assigned to KING FAISAL UNIVERSITY, Al-Ahsa (SA)
Filed by KING FAISAL UNIVERSITY, Al-Ahsa (SA)
Filed on Nov. 22, 2023, as Appl. No. 18/517,708.
Application 18/517,708 is a continuation of application No. 18/136,732, filed on Apr. 19, 2023, abandoned.
Int. Cl. A61K 36/9066 (2006.01); A61K 31/015 (2006.01); A61K 31/12 (2006.01); A61K 36/00 (2006.01); A61P 31/06 (2006.01)

CPC A61K 36/9066 (2013.01) [A61K 31/015 (2013.01); A61K 31/12 (2013.01); A61P 31/06 (2018.01); A61K 2236/11 (2013.01); A61K 2236/33 (2013.01)]

6 Claims

1. A method of enhancing active components in Curcuma longa, the method comprising:

providing a Curcuma longa rhizome;

irradiating the Curcuma longa rhizome with a laser; and

providing an ethanolic extract of the laser irradiated Curcuma longa rhizome to obtain a Curcuma longa rhizome extract of increased amounts of active ingredients of alpha-curcumene, (-)-zingiberene, caryphyllene, and beta sesquiphellandrene as compared to that of the Curcuma longa rhizome,

and wherein the Curcuma longa rhizome is irradiated with a laser having a wavelength of about 632 nm and a density power of about 5.5 mW/mm².