US 12,411,478 B2
Computing platform for bioprocess design, execution, analysis, and technology transfer
Dane Colin Pieri, Winchester, MA (US); Liu Liu, San Francisco, CA (US); Ashutosh Singhal, San Francisco, CA (US); Lucas Zulauf, Oakland, CA (US); Swathi Sundar, San Francisco, CA (US); and Vineet Gopal, San Francisco, CA (US)
Assigned to Benchling, Inc., San Francisco, CA (US)
Filed by Benchling, Inc., San Francisco, CA (US)
Filed on May 15, 2024, as Appl. No. 18/665,429.
Claims priority of provisional application 63/466,607, filed on May 15, 2023.
Prior Publication US 2024/0385600 A1, Nov. 21, 2024
Int. Cl. G05B 19/418 (2006.01)
CPC G05B 19/41865 (2013.01) 17 Claims
OG exemplary drawing
 
1. A computer-implemented method comprising:
receiving, by a bioinformatics platform though a user interface of a process development tool in communication with a process development facility, user input specifying process design parameters that specify a plurality of variations of a process for transforming one or more input materials into one or more output materials;
generating a plurality of respective recipes for the plurality of variations of the process according to the process design parameters, including automatically converting one or more parameter values of each recipe into a standardized, equipment-agnostic format;
receiving, by the bioinformatics platform from a production facility, a facilities specification that represents properties and capabilities of each item of equipment of a plurality of items of equipment at the production facility;
receiving a selection of a recipe of the plurality of generated recipes representing a variation of the plurality of variations of the process generated by the process development tool of the process development facility to be transferred to the production facility;
performing a matching process between unit operations of the selected recipe and equipment represented by the facilities specification to convert each value in the standardized, equipment-agnostic format of one or more unit operations of the recipe into an equipment-specific production task to be performed by a particular item of equipment in the production facility;
generating a production plan having a plurality of equipment-specific production tasks for the production facility; and
providing the generated production plan to the production facility, wherein equipment of the production facility is operated in accordance with the production plan.