US 12,411,103 B2
Electrode, method for manufacturing electrode, ion sensor, in-vivo component measuring device, and in-vivo component measuring method
Kenichi Uchiyama, Kobe (JP); and Junko Kojima, Kobe (JP)
Assigned to SYSMEX CORPORATION, Kobe (JP)
Filed by SYSMEX CORPORATION, Kobe (JP)
Filed on Jun. 30, 2022, as Appl. No. 17/853,991.
Application 17/853,991 is a continuation of application No. PCT/JP2020/048407, filed on Dec. 24, 2020.
Claims priority of application No. 2020-003117 (JP), filed on Jan. 10, 2020.
Prior Publication US 2022/0334077 A1, Oct. 20, 2022
Int. Cl. G01N 27/333 (2006.01); G01N 27/30 (2006.01); G01N 27/406 (2006.01)
CPC G01N 27/333 (2013.01) [G01N 27/301 (2013.01); G01N 27/406 (2013.01)] 20 Claims
OG exemplary drawing
 
1. An ion sensor comprising:
an insulating substrate;
an ion-selective electrode on the insulating substrate; and
a reference electrode on the insulating substrate, wherein the ion-selective electrode comprises:
a first internal solid layer containing metal oxide and solid electrolyte;
a first electrode material; and
an ion-selective membrane, wherein
the first internal solid layer is sandwiched between the first electrode material and the ion-selective membrane in a thickness direction of the first internal solid layer,
the ion-selective membrane comprises a multi-layer structure including a plurality of layers having the same or different compositions from each other,
the first electrode material comprises a multi-layer structure including a plurality of layers having different compositions from each other,
the first internal solid layer is provided to cover a side surface of the first electrode material,
the ion-selective membrane is provided to cover a side surface of the first internal solid layer so as not to expose the first internal solid layer,
the reference electrode comprises:
a second internal solid layer containing metal oxide and solid electrolyte;
a second electrode material; and
a salt bridge layer, wherein
the second internal solid layer is sandwiched between the second electrode material and the salt bridge layer in a thickness direction of the second internal solid layer,
the salt bridge layer comprises a multi-layer structure including a plurality of layers having different compositions from each other, and
the second electrode material comprises a multi-layer structure including a plurality of layers having different compositions from each other.