| CPC G01N 21/658 (2013.01) [B82Y 30/00 (2013.01); G01J 3/44 (2013.01)] | 19 Claims |

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1. A method of detecting hydroxycarbamide in a solution, comprising:
contacting an electrochemical sensor with the solution;
applying a potential and irradiating the electrochemical sensor in the solution; and
measuring a Raman signal of the electrochemical sensor in the solution,
wherein an intensity of the Raman signal correlates with an amount of hydroxycarbamide in the solution,
wherein the electrochemical sensor comprises:
gold coated copper oxide circular nanoplates; and
a substrate,
wherein the gold coated copper oxide circular nanoplates are coated on the substrate.
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