US 12,410,438 B2
Methods for controlling meristem size for crop improvement
Devin O′Connor, Hillsborough, NC (US); and Nathaniel Graham, Durham, NC (US)
Assigned to Pairwise Plants Services, Inc., Durham, NC (US)
Filed by Pairwise Plants Services, Inc., Durham, NC (US)
Filed on Jun. 1, 2021, as Appl. No. 17/335,264.
Claims priority of provisional application 63/033,273, filed on Jun. 2, 2020.
Prior Publication US 2021/0371873 A1, Dec. 2, 2021
Int. Cl. C12N 15/82 (2006.01); C12N 9/22 (2006.01); C12N 15/11 (2006.01)
CPC C12N 15/8262 (2013.01) [C12N 9/22 (2013.01); C12N 15/11 (2013.01); C12N 15/8213 (2013.01); C12N 2310/20 (2017.05); C12N 2800/80 (2013.01)] 8 Claims
OG exemplary drawing
 
1. A corn plant or plant part thereof comprising at least one non-natural mutation in an endogenous CORYNE (CRN) gene that encodes a wild type CRN protein, wherein the wild type CRN protein comprises a sequence having at least 95% identity to SEQ ID NO:118 and the mutation is an in-frame deletion of one or more codons that results in the deletion of one or more amino acid residues located from position 23 to position 66 with reference to amino acid position numbering of SEQ ID NO:118, or is an out-of-frame deletion that results in a premature stop codon and a truncated CRN protein, wherein the out-of-frame deletion is located in a region of the endogenous CRN gene that encodes position 23 to position 66 with reference to amino acid position numbering of SEQ ID NO:118, wherein the corn plant exhibits increased kernel row number without fasciation compared to a control corn plant devoid of the at least one non-natural mutation.