US 12,410,215 B2
Mutated glycoprotein of vesicular stomatitis virus
Aurélie Albertini, Gometz le Chatel (FR); Yves Gaudin, Paris (FR); Hélène Raux, Antony (FR); Laura Belot, Maurepas (FR); and Jovan Nikolic, Paris (FR)
Assigned to Centre National de la Recherche Scientifique (CNRS), Paris (FR); and Université Paris-Saclay, Gif sur Yvette (FR)
Filed by Centre National de la Recherche Scientifique (CNRS), Paris (FR); and Université Paris-Saclay, Gif sur Yvette (FR)
Filed on Feb. 14, 2025, as Appl. No. 19/053,784.
Application 19/053,784 is a continuation of application No. 18/629,097, filed on Apr. 8, 2024, granted, now 12,269,848.
Application 18/629,097 is a continuation of application No. 18/473,720, filed on Sep. 25, 2023, granted, now 12,030,915, issued on Jul. 9, 2024.
Application 18/473,720 is a continuation of application No. 16/649,271, granted, now 12,091,434, issued on Sep. 17, 2024, previously published as PCT/EP2018/075824, filed on Sep. 24, 2018.
Claims priority of application No. 17306255 (EP), filed on Sep. 22, 2017.
Prior Publication US 2025/0171504 A1, May 29, 2025
This patent is subject to a terminal disclaimer.
Int. Cl. C07K 14/005 (2006.01); C12N 7/00 (2006.01)
CPC C07K 14/005 (2013.01) [C12N 7/00 (2013.01); C12N 2760/20222 (2013.01); C12N 2760/20232 (2013.01); C12N 2760/20245 (2013.01); C12N 2760/20262 (2013.01)] 30 Claims
 
1. A polypeptide comprising an amino acid sequence at least 95% identical to the amino acid sequence set forth in SEQ ID NO: 1, wherein the polypeptide comprises an amino acid mutation at position 47 and an amino acid mutation at position 354.