US 12,410,113 B2
Sandalwood-type fragrance compounds
Vijayanand Chandrasekaran, Holzminden (DE); Bernd Hoelscher, Halle (DE); and Eva Kiermasch, Holzminden (DE)
Assigned to SYMRISE AG, Holzminden (DE)
Appl. No. 17/614,238
Filed by SYMRISE AG, Holzminden (DE)
PCT Filed Jun. 12, 2020, PCT No. PCT/EP2020/066394
§ 371(c)(1), (2) Date Nov. 24, 2021,
PCT Pub. No. WO2020/249794, PCT Pub. Date Dec. 17, 2020.
Claims priority of application No. PCT/EP2019/065629 (WO), filed on Jun. 13, 2019.
Prior Publication US 2022/0220051 A1, Jul. 14, 2022
Int. Cl. C07C 29/147 (2006.01); C07C 17/16 (2006.01); C07C 45/41 (2006.01); C07C 45/62 (2006.01); C07C 67/343 (2006.01); C11B 9/00 (2006.01)
CPC C07C 29/147 (2013.01) [C07C 17/16 (2013.01); C07C 45/41 (2013.01); C07C 45/62 (2013.01); C07C 67/343 (2013.01); C11B 9/0019 (2013.01)] 12 Claims
 
1. A compound of general Formula (I):

OG Complex Work Unit Chemistry
wherein
R1 represents H, an alkyl or an alkenyl group,
R2 represents an alkyl or an alkenyl group, and
R3 represents H or an alkyl group;
wherein at the position of the dotted lines there is optionally a C═C double bond or a cyclopropane ring; and
wherein the butyl chain C1 to C4 is either saturated or is unsaturated and contains one double bond in position C2/C3 or C3/C4;
wherein the compound comprises either
at least one cyclopropane substituent attached to the butyl chain in position C2 or C4; or
at least one alkenyl group attached to the butyl chain in position C2 or C4, wherein if the alkenyl group is attached to the butyl chain in position C4, the butyl chain comprises a C═C double bond in position C2/C3 or a further alkenyl group in position C2;
or at least one stereoisomer of the compound of general Formula (I); or
a compound of general Formula (VI):

OG Complex Work Unit Chemistry
wherein
R1 represents H, an alkyl or an alkenyl group,
R2 represents H or an alkyl, and
R3 represents H or an alkyl group;
wherein at the position of the dotted lines there is optionally a C═C double bond or a cyclopropane ring; and
wherein the butyl chain C1 to C4 is either saturated or is unsaturated and contains one double bond in position C2/C3 or C3/C4;
wherein the compound comprises either
at least one cyclopropane substituent attached to the butyl chain in position C2 or C4; or
at least one alkenyl group attached to the butyl chain in position C2 or C4, wherein if the alkenyl group is attached to the butyl chain in position C4, the butyl chain comprises a C═C double bond in position C2/C3 or wherein if the alkenyl group is attached to the butyl chain in position C2, the butyl chain comprises a C═C double bond in position C3/C4; or
an alkyl group attached to the butyl chain in position C2 and C4, wherein the butyl chain comprises a C═C double bond in position C2/C3;
or at least one stereoisomer of the compound of general Formula IV.